NITD-2

Modify Date: 2024-01-13 22:32:13

NITD-2 Structure
NITD-2 structure
Common Name NITD-2
CAS Number 1197896-79-9 Molecular Weight 433.48
Density N/A Boiling Point N/A
Molecular Formula C23H19N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NITD-2


NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].

 Names

Name NITD-2

 NITD-2 Biological Activity

Description NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].
Related Catalog
In Vitro NITD-2 inhibits de novo RNA synthesis[1]. NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration[1].
References

[1]. Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.

 Chemical & Physical Properties

Molecular Formula C23H19N3O4S
Molecular Weight 433.48

 Safety Information

Hazard Codes Xi