17-β-ESTRADIOL 3-METHYL ETHER

Modify Date: 2024-01-09 18:55:05

17-β-ESTRADIOL 3-METHYL ETHER structure	Common Name	17-β-ESTRADIOL 3-METHYL ETHER
	CAS Number	1474-53-9	Molecular Weight	302.40800
	Density	1.185g/cm3	Boiling Point	450.8ºC at 760mmHg
	Molecular Formula	C₁₉H₂₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	226.4ºC

Name	17-β-ESTRADIOL 3-METHYL ETHER
Synonym	More Synonyms

Density	1.185g/cm3
Boiling Point	450.8ºC at 760mmHg
Molecular Formula	C₁₉H₂₆O₃
Molecular Weight	302.40800
Flash Point	226.4ºC
Exact Mass	302.18800
PSA	49.69000
LogP	2.88300
Vapour Pressure	6.48E-09mmHg at 25°C
Index of Refraction	1.588

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7540000

CHEMICAL NAME :: Estra-1,3,5(10)-triene-16-alpha,17-beta-diol, 3-methoxy-

CAS REGISTRY NUMBER :: 1474-53-9

LAST UPDATED :: 199304

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H26-O3

MOLECULAR WEIGHT :: 302.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 5600 ug/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 15,16,1977

Hazard Codes	Xn: Harmful;
Risk Phrases	40
Safety Phrases	36/37

Estriol

CAS#:50-27-1

Dimethyl sulfate

CAS#:77-78-1

17-β-ESTRADIOL ...

CAS#:1474-53-9

Literature: Freudenhammer, Christoph; Grotemeyer, Juergen European Journal of Mass Spectrometry, 2010 , vol. 16, # 4 p. 489 - 501

Estra-1,3,5(10)...

CAS#:24721-15-1

17-β-ESTRADIOL ...

CAS#:1474-53-9

Estra-1,3,5(10)...

CAS#:3434-79-5

Literature: Sheehan et al. Journal of the American Chemical Society, 1957 , vol. 79, p. 147,148

diazomethane

CAS#:186581-53-3

Estriol

CAS#:50-27-1

17-β-ESTRADIOL ...

CAS#:1474-53-9

Literature: Schindler Helvetica Chimica Acta, 1959 , vol. 42, p. 1955,1958

Estriol

CAS#:50-27-1

Tetramethylammo...

CAS#:75-59-2

17-β-ESTRADIOL ...

CAS#:1474-53-9

Literature: MacGee; Allen Steroids, 1970 , vol. 16, # 1 p. 79 - 84

Ethanol

CAS#:64-17-5

Estra-1,3,5(10)...

CAS#:24721-15-1

acetic acid

CAS#:64-19-7

17-β-ESTRADIOL ...

CAS#:1474-53-9

Literature: Huffman Journal of Biological Chemistry, 1947 , vol. 169, p. 167,169

Estra-1,3,5(10)...

CAS#:24721-15-1

Isopropanol

CAS#:67-63-0

17-β-ESTRADIOL ...

CAS#:1474-53-9

Literature: Butenandt; Schaeffler Zeitschrift fuer Naturforschung, 1946 , vol. 1, p. 82,85

Precursor 8
CAS#:50-27-1 Estriol CAS#:77-78-1 Dimethyl sulfate CAS#:24721-15-1 Estra-1,3,5(10)... CAS#:186581-53-3 diazomethane
CAS#:75-59-2 Tetramethylammo... CAS#:64-17-5 Ethanol CAS#:64-19-7 acetic acid CAS#:67-63-0 Isopropanol
DownStream 3
CAS#:10582-05-5 Estra-1,3,5(10)... CAS#:50-27-1 Estriol CAS#:1624-62-0 Estrone 3-methy...