Lurtotecan

Modify Date: 2025-08-26 00:31:02

Lurtotecan Structure
Lurtotecan structure
Common Name Lurtotecan
CAS Number 149882-10-0 Molecular Weight 518.56100
Density 1.5g/cm3 Boiling Point 844.8ºC at 760mmHg
Molecular Formula C28H30N4O6 Melting Point N/A
MSDS N/A Flash Point 464.7ºC

 Use of Lurtotecan


Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].

 Names

Name Lurtotecan
Synonym More Synonyms

 Lurtotecan Biological Activity

Description Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].
Related Catalog
Target

Topoisomerase I

References

[1]. D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9.

 Chemical & Physical Properties

Density 1.5g/cm3
Boiling Point 844.8ºC at 760mmHg
Molecular Formula C28H30N4O6
Molecular Weight 518.56100
Flash Point 464.7ºC
Exact Mass 518.21700
PSA 106.36000
LogP 1.47400
Vapour Pressure 2.51E-30mmHg at 25°C
Index of Refraction 1.73
Storage condition -20°C

 Synonyms

GG 211
11H-1,4-Dioxino(2,3-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-9,12(8H,14H)-dione,8-ethyl-2,3-dihydro-8-hydroxy-15-((4-methyl-1-piperazinyl)methyl)-,(8S)
NX 211
(7-(4-methylpiperazinomethylene)-10,11-ethylenedioxy-20(S)-camptothecin)
OSI-211
7-[(4-methylpiperazino)methyl]-10,11-(ethylenedioxy)-(20S)-camptothecin
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