L-701252
Modify Date: 2025-08-25 14:04:40
L-701252 structure
|
Common Name | L-701252 | ||
|---|---|---|---|---|
| CAS Number | 151057-13-5 | Molecular Weight | 263.67600 | |
| Density | 1.573g/cm3 | Boiling Point | 437.3ºC at 760mmHg | |
| Molecular Formula | C13H10ClNO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 218.3ºC | |
Use of L-701252L-701252 is a potent antagonist of glycine site NMDA receptor with an IC50 of 420 nM. L-701252 provides a small degree of neuroprotection in global cerebral ischaemia[1]. |
| Name | 7-chloro-3-(cyclopropanecarbonyl)-4-hydroxy-1H-quinolin-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | L-701252 is a potent antagonist of glycine site NMDA receptor with an IC50 of 420 nM. L-701252 provides a small degree of neuroprotection in global cerebral ischaemia[1]. |
|---|---|
| Related Catalog | |
| Target |
NMDA receptor[1] |
| In Vivo | L-701252 (50 mg/kg; i.p.) provides a small non-significant protection[1]. Animal Model: 3-Months Male Mongolian gerbils (60 g)[1] Dosage: 50 mg/kg Administration: i.p. Result: Provided a small non-significant protection. |
| References |
| Density | 1.573g/cm3 |
|---|---|
| Boiling Point | 437.3ºC at 760mmHg |
| Molecular Formula | C13H10ClNO3 |
| Molecular Weight | 263.67600 |
| Flash Point | 218.3ºC |
| Exact Mass | 263.03500 |
| PSA | 70.16000 |
| LogP | 2.47980 |
| Vapour Pressure | 2.03E-08mmHg at 25°C |
| Index of Refraction | 1.694 |
| Storage condition | -20°C |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
CAS#:60064-34-8
CAS#:139422-18-7| L-701,252 |
| Tocris-0705 |