Afabicin disodium
Modify Date: 2024-01-11 11:02:57
Afabicin disodium structure
|
Common Name | Afabicin disodium | ||
|---|---|---|---|---|
| CAS Number | 1518800-29-7 | Molecular Weight | 529.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H22N3Na2O7P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Afabicin disodiumAfabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci[1]. |
| Name | Afabicin disodium |
|---|
| Description | Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Afabicin (Debio1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 inhibits FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. Debio1452 is highly active against staphylococci isolates, with MIC50 and MIC90 values of 0.015 μg/mL and 0.12 μg/mL, respectively. Debio1452 also inhibits S. aureus, with MICs of ≤0.12 μg/mL and MIC50 and MIC90 values of 0.004 μg/mL and 0.008 μg/mL, respectively[1]. |
| References |
| Molecular Formula | C23H22N3Na2O7P |
|---|---|
| Molecular Weight | 529.39 |