L-Histidine, N-formyl-

Modify Date: 2025-08-26 11:57:58

L-Histidine, N-formyl- Structure
L-Histidine, N-formyl- structure
Common Name L-Histidine, N-formyl-
CAS Number 15191-21-6 Molecular Weight 183.16500
Density 1.51g/cm3 Boiling Point 442.9ºC at 760mmHg
Molecular Formula C7H9N3O3 Melting Point 202.0 to 206.0 °C
MSDS USA Flash Point 221.6ºC

 Use of L-Histidine, N-formyl-


N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM[1][2].

 Names

Name n-formyl-l-histidine
Synonym More Synonyms

 L-Histidine, N-formyl- Biological Activity

Description N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM[1][2].
Related Catalog
References

[1]. Lepore GC, et al. Histidyl-tRNA synthetase from Salmonella typhimurium: specificity in the binding of histidine analogues. Eur J Biochem. 1975 Aug 15;56(2):369-74.

[2]. Shibatani T, et al. Crystalline L-histidine ammonia-lyase of Achromobacter liquidum. Crystallization and enzymic properties. Eur J Biochem. 1975 Jun 16;55(1):263-9.

 Chemical & Physical Properties

Density 1.51g/cm3
Boiling Point 442.9ºC at 760mmHg
Melting Point 202.0 to 206.0 °C
Molecular Formula C7H9N3O3
Molecular Weight 183.16500
Flash Point 221.6ºC
Exact Mass 183.06400
PSA 95.08000
LogP 0.17820
Vapour Pressure 1.72E-17mmHg at 25°C
Index of Refraction 58 ° (C=2, H2O)
InChIKey WFQVSLVQIFFQQN-LURJTMIESA-N
SMILES O=CNC(Cc1cnc[nH]1)C(=O)O
Water Solubility almost transparency

 Safety Information

Safety Phrases S22-S24/25
HS Code 2933290090

 Synthetic Route

~%

L-Histidine, N-formyl- Structure

L-Histidine, N-...

CAS#:15191-21-6

Literature: Justus Liebigs Annalen der Chemie, , vol. 363, p. 116

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(S)-2-Formamido-3-(1H-imidazol-4-yl)propanoic acid
N-Formyl-L-histidine
N-formyl histidine
Einecs 239-248-1
Formylhistidine
FOR-HIS-OH
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