BMY 45778
Modify Date: 2025-09-12 10:42:15
BMY 45778 structure
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Common Name | BMY 45778 | ||
|---|---|---|---|---|
| CAS Number | 152575-66-1 | Molecular Weight | 438.43 | |
| Density | 1.298g/cm3 | Boiling Point | 659.9ºC at 760 mmHg | |
| Molecular Formula | C26H18N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 352.9ºC | |
Use of BMY 45778BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor[1]. |
| Name | bmy 45778 |
|---|---|
| Synonym | More Synonyms |
| Description | BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor[1]. |
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| Related Catalog | |
| References |
| Density | 1.298g/cm3 |
|---|---|
| Boiling Point | 659.9ºC at 760 mmHg |
| Molecular Formula | C26H18N2O5 |
| Molecular Weight | 438.43 |
| Flash Point | 352.9ºC |
| Exact Mass | 438.12200 |
| PSA | 98.59000 |
| LogP | 5.79400 |
| Vapour Pressure | 2.59E-18mmHg at 25°C |
| Index of Refraction | 1.617 |
| InChIKey | DSRSEEYZGWTODH-UHFFFAOYSA-N |
| SMILES | O=C(O)COc1cccc(-c2ocnc2-c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 |
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Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
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Name: Thermal Shift Assay. Domain start/stop: M626-G740
Source: ChEMBL
Target: Peregrin
External Id: CHEMBL4650107
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Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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|
Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library
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Name: Thermal Shift Assay. Domain: start/stop: M1-S360
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL5067266
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Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5063550
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Name: Thermal Shift Assay. Domain: start/stop: M26-R383
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL5065589
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| Tocris-1442 |
| 2-[3-[4-(4,5-diphenyl-1,3-oxazol-2-yl)-1,3-oxazol-5-yl]phenoxy]acetic acid |