AD-35 hydrochloride

Modify Date: 2024-01-07 17:19:07

AD-35 hydrochloride Structure
AD-35 hydrochloride structure
Common Name AD-35 hydrochloride
CAS Number 1531586-62-5 Molecular Weight 441.956
Density N/A Boiling Point N/A
Molecular Formula C24H28ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AD-35 hydrochloride


A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.

 Names

Name AD-35 hydrochloride

 AD-35 hydrochloride Biological Activity

Description A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.
References References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE)

 Chemical & Physical Properties

Molecular Formula C24H28ClN3O3
Molecular Weight 441.956