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1531586-64-7

1531586-64-7 structure
1531586-64-7 structure
  • Name: AD-35 phosphate
  • Chemical Name: AD-35 phosphate
  • CAS Number: 1531586-64-7
  • Molecular Formula: C24H27N3O3.H3O4P
  • Molecular Weight: 503.485
  • Create Date: 2020-01-12 18:03:22
  • Modify Date: 2024-04-02 17:53:29
  • A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.

Name AD-35 phosphate
Description A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.
References References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE)
Molecular Formula C24H27N3O3.H3O4P
Molecular Weight 503.485