AD-35 phosphate structure
|
Common Name | AD-35 phosphate | ||
---|---|---|---|---|
CAS Number | 1531586-64-7 | Molecular Weight | 503.485 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C24H27N3O3.H3O4P | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of AD-35 phosphateA donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
Name | AD-35 phosphate |
---|
Description | A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
---|---|
References | References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE) |
Molecular Formula | C24H27N3O3.H3O4P |
---|---|
Molecular Weight | 503.485 |