carboxyebselen

Modify Date: 2024-02-03 11:57:30

Use of carboxyebselen

Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1].

Name	4-(3-oxo-1,2-benzoselenazol-2-yl)benzoic acid
Synonym	More Synonyms

Description	Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> NO Synthase
In Vivo	Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta[1].
References	[1]. Hatchett RJ, et al. Carboxyebselen a potent and selective inhibitor of endothelial nitric oxide synthase. J Physiol Pharmacol. 1994;45(1):55-67.

(2-carbonochlor...

CAS#:1441-85-6

4-Aminobenzoic acid

CAS#:150-13-0

~96%

carboxyebselen

CAS#:153871-75-1

Literature: Mlochowski, Jacek; Kloc, Krystian; Syper, Ludwik; Inglot, Anna D.; Piasecki, Egbert Liebigs Annalen der Chemie, 1993 , # 12 p. 1239 - 1244

4-(3-Oxo-1,2-benzoselenazol-2(3H)-yl)benzoic acid

Carboxyebselen

4-(1,2-benzisoselenazol-3-(2H)-one-2-yl)benzoic acid

Hooc-ebs

Benzoic acid,4-(3-oxo-1,2-benzisoselenazol-2(3H)-yl)

2-(carboxyphenyl)-1,2-benzisoselenazol-3(2H)-one

4-(2,3-dihydro-3-oxo-1,2-benzisoselenazol-2-yl)benzoic acid

Get all suppliers and price by the below link:

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3