Prunetrin

Modify Date: 2024-01-06 08:22:48

Prunetrin Structure
Prunetrin structure
Common Name Prunetrin
CAS Number 154-36-9 Molecular Weight 446.40400
Density N/A Boiling Point N/A
Molecular Formula C22H22O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Prunetrin


Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2].

 Names

Name 3-{4-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]phenyl}-5-hydroxy-7-methoxychromen-4-one
Synonym More Synonyms

 Prunetrin Biological Activity

Description Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2].
Related Catalog
In Vitro Prunetin inhibits LPS-induced nitric oxide and prostaglandin E2 production through the suppression of iNOS and COX-2 at the transcriptional level[1]. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells[2].
References

[1]. Yang G, et al. Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway. Food Chem Toxicol. 2013;58:124-132.

[2]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018;106:1469-1477.

 Chemical & Physical Properties

Molecular Formula C22H22O10
Molecular Weight 446.40400
Exact Mass 446.12100
PSA 159.05000
LogP 0.35290

 Synonyms

3-(4-β-D-glucopyranosyloxy-phenyl)-5-hydroxy-7-methoxy-chromen-4-one
5-Hydroxy-7-methoxy-3-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-chromen-4-one
prunetin-4'-O-β-D glucopyranoside
prunetrin
Prunetin 4'-O-β-D-glucopyranoside
prunetin 4'-O-[β-D-glucopyranoside]
4',5-dihydroxy-7-methoxyisoflavone-4'-O-β-D-glucopyranoside