Inosine,2-chloro-6-O-methyl- (9CI)
Inosine,2-chloro-6-O-methyl- (9CI) structure
|
Common Name | Inosine,2-chloro-6-O-methyl- (9CI) | ||
|---|---|---|---|---|
| CAS Number | 15465-92-6 | Molecular Weight | 316.70 | |
| Density | 1.95g/cm3 | Boiling Point | 587.8ºC at 760mmHg | |
| Molecular Formula | C11H13ClN4O5 | Melting Point | 140 °C(Solv: isopropanol (67-63-0)) | |
| MSDS | N/A | Flash Point | 309.3ºC | |
Use of Inosine,2-chloro-6-O-methyl- (9CI)2-Chloro-6-methoxypurine riboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Chloro-6-O-methyl-inosine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Chloro-6-methoxypurine riboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2]. |
|---|---|
| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.95g/cm3 |
|---|---|
| Boiling Point | 587.8ºC at 760mmHg |
| Melting Point | 140 °C(Solv: isopropanol (67-63-0)) |
| Molecular Formula | C11H13ClN4O5 |
| Molecular Weight | 316.70 |
| Flash Point | 309.3ºC |
| Exact Mass | 316.05700 |
| PSA | 122.75000 |
| Vapour Pressure | 1.16E-14mmHg at 25°C |
| Index of Refraction | 1.784 |
| InChIKey | QFGKCCNEHWKCTD-UHFFFAOYSA-N |
| SMILES | COc1nc(Cl)nc2c1ncn2C1OC(CO)C(O)C1O |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~%
Inosine,2-chlor... CAS#:15465-92-6 |
| Literature: Schaeffer; Thomas Journal of the American Chemical Society, 1958 , vol. 80, p. 3738,3741 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
|---|---|
| DownStream 5 | |
CAS#:13364-95-9
CAS#:15763-11-8
CAS#:146-77-0
CAS#:24723-77-1
CAS#:51385-35-4This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-(2-chloro-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does 2-Chloro-6-O-methyl-inosine have? |
| A: English synonyms of 2-Chloro-6-O-methyl-inosine: 2-(2-chloro-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol. |
| Q: What is the melting point of 2-Chloro-6-O-methyl-inosine? |
| A: Melting point of 2-Chloro-6-O-methyl-inosine is 140 °C(Solv: isopropanol (67-63-0)). |
| Q: What are the downstream products of 2-Chloro-6-O-methyl-inosine? |
| A: Related downstream products(CAS) of 2-Chloro-6-O-methyl-inosine: 13364-95-9;15763-11-8;146-77-0;24723-77-1;51385-35-4. |
| Q: What is the English name of 2-Chloro-6-O-methyl-inosine? |
| A: The English name of 2-Chloro-6-O-methyl-inosine is 2-Chloro-6-O-methyl-inosine. |
| Q: What is the molecular formula of 2-Chloro-6-O-methyl-inosine? |
| A: Molecular formula of 2-Chloro-6-O-methyl-inosine is C11H13ClN4O5. |
| Q: What is the molecular weight of 2-Chloro-6-O-methyl-inosine? |
| A: Molecular weight of 2-Chloro-6-O-methyl-inosine is 316.70. |
| Q: What is the SMILES notation of 2-Chloro-6-O-methyl-inosine? |
| A: SMILES notation of 2-Chloro-6-O-methyl-inosine is COc1nc(Cl)nc2c1ncn2C1OC(CO)C(O)C1O. |
| Q: What is the boiling point of 2-Chloro-6-O-methyl-inosine? |
| A: Boiling point of 2-Chloro-6-O-methyl-inosine is 587.8ºC at 760mmHg. |
| Q: What are the upstream materials of 2-Chloro-6-O-methyl-inosine? |
| A: Related upstream materials(CAS) of 2-Chloro-6-O-methyl-inosine: 124-41-4. |
| Q: What is the InChIKey of 2-Chloro-6-O-methyl-inosine? |
| A: InChIKey of 2-Chloro-6-O-methyl-inosine is QFGKCCNEHWKCTD-UHFFFAOYSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |