2-Hydrazinyl-adenosine
Modify Date: 2024-01-19 15:08:40
2-Hydrazinyl-adenosine structure
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Common Name | 2-Hydrazinyl-adenosine | ||
|---|---|---|---|---|
| CAS Number | 15763-11-8 | Molecular Weight | 297.27 | |
| Density | 2.29±0.1 g/cm3(Predicted) | Boiling Point | 583.1±60.0 °C(Predicted) | |
| Molecular Formula | C10H15N7O4 | Melting Point | 208-210ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2-Hydrazinyl-adenosine2-Hydrazinyl-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 2-Hydrazino Adenosine |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Hydrazinyl-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.29±0.1 g/cm3(Predicted) |
|---|---|
| Boiling Point | 583.1±60.0 °C(Predicted) |
| Melting Point | 208-210ºC |
| Molecular Formula | C10H15N7O4 |
| Molecular Weight | 297.27 |
| Exact Mass | 297.11900 |
| PSA | 177.59000 |
| Index of Refraction | 2.002 |
| Storage condition | 2-8°C |
| Hazard Codes | Xn |
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~94%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: RELIABLE BIOPHARMACEUTICAL CORPORATION; WOOLDRIDGE, Luzviminda, T.; MA, Chun; NADJI, Sourena Patent: WO2012/149196 A1, 2012 ; Location in patent: Page/Page column 17 ; |
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~82%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: CV THERAPEUTICS, INC. Patent: WO2008/143667 A1, 2008 ; Location in patent: Page/Page column 20-21 ; WO 2008/143667 A1 |
|
~83%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: Van Tilburg, Erica W.; Von Frijtag Drabbe Kuenzel, Jacobien; De Groote, Miriam; IJzerman, Ad P. Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 420 - 429 |
|
~88%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: Niiya; Olsson; Thompson; Silvia; Ueeda Journal of Medicinal Chemistry, 1992 , vol. 35, # 24 p. 4557 - 4561 |
|
~%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: Schaeffer; Thomas Journal of the American Chemical Society, 1958 , vol. 80, p. 3738,3741 |
|
~%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: El-Tayeb, Ali; Gollos, Sabrina Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 2 p. 436 - 447 |
|
~%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: El-Tayeb, Ali; Gollos, Sabrina Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 2 p. 436 - 447 |
|
~%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: El-Tayeb, Ali; Gollos, Sabrina Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 2 p. 436 - 447 |
|
~%
2-Hydrazinyl-ad... CAS#:15763-11-8 |
| Literature: El-Tayeb, Ali; Gollos, Sabrina Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 2 p. 436 - 447 |
![9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE structure](https://www.chemsrc.com/caspic/019/3056-18-6.png)
| Precursor 9 | |
|---|---|
| DownStream 2 | |
CAS#:59587-07-4
CAS#:58-61-7| (2R,3R,4S,5R)-2-(6-amino-2-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |