RU58841

Modify Date: 2024-01-04 22:49:03

RU58841 structure	Common Name	RU58841
	CAS Number	154992-24-2	Molecular Weight	369.338
	Density	1.4±0.1 g/cm3	Boiling Point	493.6±55.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₈F₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	252.3±31.5 °C

Use of RU58841

RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 (PSK-3841) has a dramatic effect on hair regrowth.

Name	4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Synonym	More Synonyms

Description	RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 (PSK-3841) has a dramatic effect on hair regrowth.
Related Catalog	Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Endocrinology
Target	Androgen receptor
References	[1]. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702. [2]. Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12. [3]. Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60. [4]. Blaschke T, Kankate L, Kramer KD.Structure and dynamics of drug-carrier systems as studied by parelectric spectroscopy.Adv Drug Deliv Rev. 2007 Jul 10;59(6):403-10. Epub 2007 May 3. [5]. Matias JR, Gaillard M.Local inhibition of sebaceous gland growth by topically applied RU 58841.Ann N Y Acad Sci. 1995 Jun 12;761:56-65.

Density	1.4±0.1 g/cm3
Boiling Point	493.6±55.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₈F₃N₃O₃
Molecular Weight	369.338
Flash Point	252.3±31.5 °C
Exact Mass	369.130035
PSA	84.64000
LogP	1.39
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.560
Storage condition	2-8°C

Hazard Codes	Xi
HS Code	2933990090

4-Bromobutyl acetate

CAS#:4753-59-7

4-(4,4-Dimethyl...

CAS#:143782-20-1

~77%

RU58841

CAS#:154992-24-2

Literature: Leonard, Matthew J.; Lingham, Anthony R.; Niere, Julie O.; Jackson, Neale R. C.; McKay, Peter G.; Huegel, Helmut M. RSC Advances, 2014 , vol. 4, # 27 p. 14143 - 14148

4-Amino-2-(trif...

CAS#:654-70-6

RU58841

CAS#:154992-24-2

Literature: RSC Advances, , vol. 4, # 27 p. 14143 - 14148

p-cyano-m-trifl...

CAS#:1259327-69-9

RU58841

CAS#:154992-24-2

Literature: RSC Advances, , vol. 4, # 27 p. 14143 - 14148

Precursor 3
CAS#:4753-59-7 4-Bromobutyl acetate CAS#:143782-20-1 4-(4,4-Dimethyl... CAS#:654-70-6 4-Amino-2-(trif...
DownStream 1
CAS#:4427-97-8 dicyclohexyl ca...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Ru-58841

4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxy-butyl)-1-imidazolidinyl)-2-(trifluoromethyl)-benzonitrile

4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile

Benzonitrile, 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)-

T5NVNV EHJ A4Q CR DCN CXFFF& E1 E1

4-(3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

RU58841

RU 58841

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: RU58841
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: RU58841
Price: $300.0/100mg $600.0/250mg $1200.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: RU58841
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

RU58841 suppliers

Price: ￥748.8/1mg

Reference only. check more RU58841 price

RU58841

Use of RU58841

Names

RU58841 Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms