Resorufin butyrate

Modify Date: 2024-01-13 13:09:08

Resorufin butyrate Structure
Resorufin butyrate structure
Common Name Resorufin butyrate
CAS Number 15585-42-9 Molecular Weight 283.27900
Density 1.31g/cm3 Boiling Point 428.7ºC at 760 mmHg
Molecular Formula C16H13NO4 Melting Point 136-138ºC(lit.)
MSDS Chinese USA Flash Point 194.5ºC

 Use of Resorufin butyrate


Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm)[1][2][3].

 Names

Name Resorufin butyrate
Synonym More Synonyms

 Resorufin butyrate Biological Activity

Description Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm)[1][2][3].
Related Catalog
Target

Triglyceride lipases, cholinesterase[1]

In Vitro Resorufin butyrate (2.3 μM) displays a linear increase in fluorescence over 60 min (conducted in 384-well plates using 12 nM of bLPL enzyme and substrate in PBS, pH 7.5, 5% DMSO)[1].
References

[1]. J Biomol Screen, et al. Resorufin butyrate as a soluble and monomeric high-throughput substrate for a triglyceride lipase. J Biomol Screen. 2012 Feb;17(2):245-51.

[2]. Guilbault, G.G., et al. Resorufin butyrate and indoxyl acetate as fluorogenic substrates for chloinesterase. Anal Chem. 1965 Jan;37:120-3.

[3]. J.Hofmann, et al. Immobilized enzyme kinetics analyzed by flow-through microfluorimetry : Resorufin-β-d-galactopyranoside as a New Fluorogenic Substrate for β-Galactosidase. Anal. Chim. Acta 163, 67-72 (1984).

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 428.7ºC at 760 mmHg
Melting Point 136-138ºC(lit.)
Molecular Formula C16H13NO4
Molecular Weight 283.27900
Flash Point 194.5ºC
Exact Mass 283.08400
PSA 69.40000
LogP 2.99830
Vapour Pressure 1.48E-07mmHg at 25°C
Index of Refraction 1.62

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles1

More Articles
Mapping substrate selectivity of lipases from thermophilic fungi

J. Mol. Catal., B Enzym. 49 , 104-112, (2007)

 Synonyms

(7-oxophenoxazin-3-yl) butanoate