2,4-Diaminopyrimidine
2,4-Diaminopyrimidine structure
|
Common Name | 2,4-Diaminopyrimidine | ||
|---|---|---|---|---|
| CAS Number | 156-81-0 | Molecular Weight | 110.117 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 401.7±37.0 °C at 760 mmHg | |
| Molecular Formula | C4H6N4 | Melting Point | 143-147 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 225.6±13.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2,4-Diaminopyrimidine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 401.7±37.0 °C at 760 mmHg |
| Melting Point | 143-147 °C(lit.) |
| Molecular Formula | C4H6N4 |
| Molecular Weight | 110.117 |
| Flash Point | 225.6±13.7 °C |
| Exact Mass | 110.059242 |
| PSA | 77.82000 |
| LogP | -0.64 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.695 |
| InChIKey | YAAWASYJIRZXSZ-UHFFFAOYSA-N |
| SMILES | Nc1ccnc(N)n1 |
| Storage condition | Refrigerator (+4°C) |
| Water Solubility | 840 g/L (25 ºC) |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2942000000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 5 | |
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CAS#:74638-76-9![7-AMINOIMIDAZO[1,2-A]PYRIMIDINE structure](https://image.chemsrc.com/caspic/363/462651-80-5.png)
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CAS#:591227-12-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.
Neuropharmacology 99 , 422-31, (2015) Nitric oxide (NO) is involved in desensitization of μ-opioid receptors (MOR). We used extracellular recordings in vitro to unmask the NO-dependent pathways involved in MOR desensitization in the rat l... |
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Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.
Eur. J. Med. Chem. 96 , 269-80, (2015) Therapeutics of metastatic or triple-negative breast cancer are still challenging in clinical. Herein we demonstrated the design and optimization of a series of hybrid of 2,4-diaminopyrimidine and ary... |
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Cocrystals of 6-methyl-2-thiouracil: presence of the acceptor-donor-acceptor/donor-acceptor-donor synthon.
Acta Crystallogr. C Struct. Chem. 71(Pt 3) , 229-38, (2015) The results of seven cocrystallization experiments of the antithyroid drug 6-methyl-2-thiouracil (MTU), C(5)H(6)N(2)OS, with 2,4-diaminopyrimidine, 2,4,6-triaminopyrimidine and 6-amino-3H-isocytosine ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2,4(1H,3H)-Pyrimidinediimine |
| 2,4-Pyrimidinediamine |
| MFCD00038023 |
| 2,3-DIPHENYL-6-NITROQUINOXALINE |
| 2,4-diamino-pyrimidine |
| pyrimidinediamine |
| 2,6-diaminopyrimidine |
| 2,4-Diaminopyrimidine |
| Pyrimidine,2,4-diamino |
| diamino-pyrimidine |
| DAP |
| diaminopyrimidine |
| 2,4-diaminopyridine |
| Pyrimidine-2,4-diamine |
| pyrimidine-2,4-diyldiamine |
| EINECS 205-862-3 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for 2,4-Diaminopyrimidine? |
| A: Safety information for 2,4-Diaminopyrimidine: S26-S37/39. |
| Q: How is the water solubility of 2,4-Diaminopyrimidine? |
| A: Water solubility of 2,4-Diaminopyrimidine: 840 g/L (25 ºC). |
| Q: What is the molecular weight of 2,4-Diaminopyrimidine? |
| A: Molecular weight of 2,4-Diaminopyrimidine is 110.117. |
| Q: What are the storage conditions for 2,4-Diaminopyrimidine? |
| A: Storage conditions for 2,4-Diaminopyrimidine: Refrigerator (+4°C). |
| Q: What is the polar surface area (PSA) of 2,4-Diaminopyrimidine? |
| A: Polar surface area (PSA) of 2,4-Diaminopyrimidine is 77.82000. |
| Q: What is the LogP of 2,4-Diaminopyrimidine? |
| A: LogP of 2,4-Diaminopyrimidine is -0.64. |
| Q: What is the English name of 2,4-Diaminopyrimidine? |
| A: The English name of 2,4-Diaminopyrimidine is 2,4-Diaminopyrimidine. |
| Q: What is the SMILES notation of 2,4-Diaminopyrimidine? |
| A: SMILES notation of 2,4-Diaminopyrimidine is Nc1ccnc(N)n1. |
| Q: What is the melting point of 2,4-Diaminopyrimidine? |
| A: Melting point of 2,4-Diaminopyrimidine is 143-147 °C(lit.). |
| Q: What is the boiling point of 2,4-Diaminopyrimidine? |
| A: Boiling point of 2,4-Diaminopyrimidine is 401.7±37.0 °C at 760 mmHg. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |