6-Chloropyrimidine-2,4-diamine
6-Chloropyrimidine-2,4-diamine structure
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Common Name | 6-Chloropyrimidine-2,4-diamine | ||
|---|---|---|---|---|
| CAS Number | 156-83-2 | Molecular Weight | 144.562 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 438.3±48.0 °C at 760 mmHg | |
| Molecular Formula | C4H5ClN4 | Melting Point | 199-202 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 218.9±29.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: 4-Chloro-2,6-diaminopyrimidine, also known as 2,4-diamino-6-chloropyrimidine, has a CAS number of 156-83-2 and a molecular formula of C4H5ClN4 with a molecular weight of 144.562. It is a white crystalline solid with a熔点 of 199-202°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Chloro-2,6-diaminopyrimidine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 438.3±48.0 °C at 760 mmHg |
| Melting Point | 199-202 °C(lit.) |
| Molecular Formula | C4H5ClN4 |
| Molecular Weight | 144.562 |
| Flash Point | 218.9±29.6 °C |
| Exact Mass | 144.020279 |
| PSA | 77.82000 |
| LogP | 0.45 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.702 |
| InChIKey | QJIUMVUZDYPQRT-UHFFFAOYSA-N |
| SMILES | Nc1cc(Cl)nc(N)n1 |
| Storage condition | -20°C Freezer |
| Water Solubility | slightly soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29335995 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: ISTITUTO FARMACOLOGICO SERONO SpA Patent: EP295218 A1, 1988 ; |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 19, p. 917 - 921 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Journal of the American Chemical Society, , vol. 72, p. 1914,1917 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2234 Chemische Berichte, , vol. 34, p. 3363 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2234 Chemische Berichte, , vol. 34, p. 3363 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2234 Chemische Berichte, , vol. 34, p. 3363 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2227 Chemische Berichte, , vol. 34, p. 3363 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2234 Chemische Berichte, , vol. 34, p. 3363 |
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6-Chloropyrimid... CAS#:156-83-2 |
| Literature: Chemische Berichte, , vol. 36, p. 2234 Chemische Berichte, , vol. 34, p. 3363 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 10 | |
CAS#:3270-97-1
CAS#:35139-67-4
CAS#:101724-61-2
CAS#:116436-03-4
CAS#:3308-24-5
CAS#:34960-71-9
CAS#:17419-08-8
CAS#:156-81-0
CAS#:24867-26-3
CAS#:113674-67-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Experimentally measured binding affinity data (Ki) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Ki for protein-ligand complexes
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Esch...
Source: ChEMBL
Target: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
External Id: CHEMBL4425335
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Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 6-Chloro-2,4-pyrimidinediamine |
| 6-chloro-2,4-diamino-pyrimidine |
| 6-chloro-4-pyrimidinediamine |
| EINECS 205-863-9 |
| 4-chloro-2,6-diamino-pyrimidine |
| 6-Chloro-2,4-diaminopyrimidine |
| 2,6-Diamino-4-chloropyrimidine |
| 4-Chloro-2-6-Diaminopyrimide |
| 4-Chloro-2,6-diamino |
| 2,4-Diamino-6-chloropyrimidine |
| 4-DiaMino-6-chloropyriMidine |
| 6-chloropyrimidine-2,4-diamine |
| 2,4-Diamino-6-Chloro Pyridine |
| MFCD00006097 |
| 2,6-diamino-4-chloro-pyrimidine |
| 4-Chloro-2,6-pyrimidinediamine |
| 6-Chloro-pyrimidine-2,4-diamine |
| 2-amino-4-chloro-6-methyl pyrimidine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of 4-Chloro-2,6-diaminopyrimidine? |
| A: Related downstream products(CAS) of 4-Chloro-2,6-diaminopyrimidine: 3270-97-1;35139-67-4;101724-61-2;116436-03-4;3308-24-5;34960-71-9;17419-08-8;156-81-0;24867-26-3;113674-67-2. |
| Q: What is the boiling point of 4-Chloro-2,6-diaminopyrimidine? |
| A: Boiling point of 4-Chloro-2,6-diaminopyrimidine is 438.3±48.0 °C at 760 mmHg. |
| Q: What is the LogP of 4-Chloro-2,6-diaminopyrimidine? |
| A: LogP of 4-Chloro-2,6-diaminopyrimidine is 0.45. |
| Q: What is the SMILES notation of 4-Chloro-2,6-diaminopyrimidine? |
| A: SMILES notation of 4-Chloro-2,6-diaminopyrimidine is Nc1cc(Cl)nc(N)n1. |
| Q: What are the upstream materials of 4-Chloro-2,6-diaminopyrimidine? |
| A: Related upstream materials(CAS) of 4-Chloro-2,6-diaminopyrimidine: 14989-30-1;56-06-4;83170-03-0;100643-27-4;10132-07-7;56-05-3;3764-01-0;7664-41-7. |
| Q: What is the molecular weight of 4-Chloro-2,6-diaminopyrimidine? |
| A: Molecular weight of 4-Chloro-2,6-diaminopyrimidine is 144.562. |
| Q: What is the melting point of 4-Chloro-2,6-diaminopyrimidine? |
| A: Melting point of 4-Chloro-2,6-diaminopyrimidine is 199-202 °C(lit.). |
| Q: What are the storage conditions for 4-Chloro-2,6-diaminopyrimidine? |
| A: Storage conditions for 4-Chloro-2,6-diaminopyrimidine: -20°C Freezer. |
| Q: How is the water solubility of 4-Chloro-2,6-diaminopyrimidine? |
| A: Water solubility of 4-Chloro-2,6-diaminopyrimidine: slightly soluble. |
| Q: What is the safety information for 4-Chloro-2,6-diaminopyrimidine? |
| A: Safety information for 4-Chloro-2,6-diaminopyrimidine: S26-S24/25. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |