2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID

Modify Date: 2024-01-04 19:16:25

2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID structure	Common Name	2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID
	CAS Number	15641-58-4	Molecular Weight	142.19600
	Density	0.999 g/cm3	Boiling Point	204.8ºC at 760 mmHg
	Molecular Formula	C₈H₁₄O₂	Melting Point	120-121 °C(lit.)
	MSDS	Chinese USA	Flash Point	97.5ºC
	Symbol	GHS07	Signal Word	Warning

Name	2,2,3,3-tetramethylcyclopropanecarboxylic acid
Synonym	More Synonyms

Density	0.999 g/cm3
Boiling Point	204.8ºC at 760 mmHg
Melting Point	120-121 °C(lit.)
Molecular Formula	C₈H₁₄O₂
Molecular Weight	142.19600
Flash Point	97.5ºC
Exact Mass	142.09900
PSA	37.30000
LogP	1.75320
Vapour Pressure	0.106mmHg at 25°C
Index of Refraction	1.454

MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2916209090

Precursor 9
CAS#:563-79-1 tetramethylethylene CAS#:771-10-8 Ethyl 2,2,3,3-t... CAS#:2415-95-4 Methyl 2,2,3,3-... CAS#:623-73-4 EDA
CAS#:39515-41-8 fenpropathrin [ANSI] CAS#:504-64-3 carbon suboxide CAS#:917-64-6 METHYLMAGNESIUM... CAS#:3664-56-0 1,3,3-Trimethyl...
CAS#:124-38-9 Carbon dioxide
DownStream 5
CAS#:39515-41-8 fenpropathrin [ANSI] CAS#:24303-61-5 2,2,3,3-Tetrame... CAS#:771-10-8 Ethyl 2,2,3,3-t... CAS#:55265-53-7 CYCLOPROPANECAR...
CAS#:60802-86-0 1-(2,2,3,3-tetr...

HS Code	2916209090
Summary	2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.

Epilepsy Res. 98(2-3) , 238-46, (2012)

Valproic acid (VPA) is a major antiepileptic drug (AED) that is less potent than other AEDs. 2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA) is an inactive cyclopropyl analogue of VPA that serve...

Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.

J. Med. Chem. 52 , 2233-42, (2009)

2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA, 4) is a cyclic analogue of the antiepileptic drug (AED) valproic acid (VPA) (1). alpha-F, alpha-Cl, alpha-Br, and alpha-methyl derivatives of 4 an...

Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives.

Biochem. Pharmacol. 69(10) , 1501-8, (2005)

The tumor cells toxicity of the antiepileptic drug valproic acid (VPA) has been associated with the inhibition of histone deacetylases (HDACs). We have assessed, in comparison to VPA, the HDACs inhibi...

2,2,3,3-tetramethylcyclopropane-1-carboxylic acid

MFCD00011538

2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID