Aviculin

Modify Date: 2025-08-25 21:22:07

Aviculin structure	Common Name	Aviculin
	CAS Number	156765-33-2	Molecular Weight	506.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₄O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Aviculin

Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1].

Name	Aviculin

Description	Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Apoptosis >> Caspase Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	Caspase-9 Caspase-7 Bcl-2 Bax PARP
References	[1]. Lee D, et al. Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway. Molecules. 2020 Apr 8;25(7):1708.

Molecular Formula	C₂₆H₃₄O₁₀
Molecular Weight	506.54
InChIKey	FPJFPMQEUVMUKU-CDDCGRQRSA-N
SMILES	COc1cc(C2c3cc(O)c(OC)cc3CC(CO)C2COC2OC(C)C(O)C(O)C2O)ccc1O

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Aviculin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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Aviculin

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Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.