Aviculin

Modify Date: 2024-07-21 10:49:34

Aviculin structure	Common Name	Aviculin
	CAS Number	156765-33-2	Molecular Weight	506.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₄O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Aviculin

Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1].

Name	Aviculin

Description	Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Apoptosis >> Caspase Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	Caspase-9 Caspase-7 Bcl-2 Bax PARP
References	[1]. Lee D, et al. Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway. Molecules. 2020 Apr 8;25(7):1708.

Molecular Formula	C₂₆H₃₄O₁₀
Molecular Weight	506.54

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Aviculin
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Purity: 98.0%
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