2,2',5,5'-Tetrachloro-4,4'-biphenyldiamine

Modify Date: 2024-01-06 03:11:28

2,2',5,5'-Tetrachloro-4,4'-biphenyldiamine structure	Common Name	2,2',5,5'-Tetrachloro-4,4'-biphenyldiamine
	CAS Number	15721-02-5	Molecular Weight	322.017
	Density	1.6±0.1 g/cm3	Boiling Point	408.2±40.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₈Cl₄N₂	Melting Point	135-140 °C(lit.)
	MSDS	N/A	Flash Point	200.7±27.3 °C

Name	2,2',5,5'-Tetrachlorobenzidine
Synonym	More Synonyms

Density	1.6±0.1 g/cm3
Boiling Point	408.2±40.0 °C at 760 mmHg
Melting Point	135-140 °C(lit.)
Molecular Formula	C₁₂H₈Cl₄N₂
Molecular Weight	322.017
Flash Point	200.7±27.3 °C
Exact Mass	319.944153
PSA	52.04000
LogP	4.83
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.687
Storage condition	-70°C

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD1751000

CHEMICAL NAME :: Benzidine, 2,2',5,5'-tetrachloro-

CAS REGISTRY NUMBER :: 15721-02-5

BEILSTEIN REFERENCE NO. :: 3364286

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C12-H8-Cl4-N2

MOLECULAR WEIGHT :: 322.02

WISWESSER LINE NOTATION :: ZR BG EG DR DZ CG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 54 mg/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - lymphoma, including Hodgkin's disease

REFERENCE :: JMEJAS Jikeikai Medical Journal. (Jikei Univ. School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1954- Volume(issue)/page/year: 25,123,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 36 mg/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - lymphoma, including Hodgkin's disease

REFERENCE :: JMEJAS Jikeikai Medical Journal. (Jikei Univ. School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1954- Volume(issue)/page/year: 25,123,1978

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 gm/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

REFERENCE :: IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,141,1982

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 gm/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,141,1982 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,141,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,141,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Hazard Codes	T
Risk Phrases	61
Safety Phrases	53-45
WGK Germany	3
RTECS	DD1751000
HS Code	2921590090

N-(4-amino-2,5-...

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2,2',5,5'-Tetra...

CAS#:15721-02-5

Literature: Journal of Scientific and Industrial Research, Section B: Physical Sciences, , vol. 6, p. 103,106

1,2-bis(2,5-dic...

CAS#:60696-76-6

2,2',5,5'-Tetra...

CAS#:15721-02-5

Literature: Journal of Scientific and Industrial Research, Section B: Physical Sciences, , vol. 5, p. 75

Hydrochloric acid

CAS#:7647-01-0

N-(4-amino-2,5-...

CAS#:6392-96-7

2,2',5,5'-Tetra...

CAS#:15721-02-5

Literature: Journal of Scientific and Industrial Research, , vol. 6B, p. 103,105

Precursor 3
CAS#:60696-76-6 1,2-bis(2,5-dic... CAS#:6392-96-7 N-(4-amino-2,5-... CAS#:7647-01-0 Hydrochloric acid
DownStream 4
CAS#:35694-04-3 2,2',3,3',5,5'-... CAS#:35693-99-3 2,2',5,5'-PCB CAS#:35694-08-7 OCTACHLOROBIPHENYL CAS#:35065-27-1 PCB-153

HS Code	2921590090
Summary	2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%