PCB-153

Modify Date: 2025-08-20 19:15:10

PCB-153 structure	Common Name	PCB-153
	CAS Number	35065-27-1	Molecular Weight	360.878
	Density	1.6±0.1 g/cm3	Boiling Point	396.2±37.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₄Cl₆	Melting Point	103-104ºC
	MSDS	Chinese USA	Flash Point	193.2±23.9 °C
	Symbol	GHS08, GHS09	Signal Word	Warning

Name	2,2',4,4',5,5'-hexachlorobiphenyl
Synonym	More Synonyms

Density	1.6±0.1 g/cm3
Boiling Point	396.2±37.0 °C at 760 mmHg
Melting Point	103-104ºC
Molecular Formula	C₁₂H₄Cl₆
Molecular Weight	360.878
Flash Point	193.2±23.9 °C
Exact Mass	357.844421
LogP	6.83
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.627
Storage condition	2-8°C
Stability	Thermally stable and resistant to both oxidation and biological degradation.

PCB-153 MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV5350000

CHEMICAL NAME :: 1,1'-Biphenyl, 2,2',4,4',5,5'-hexachloro-

CAS REGISTRY NUMBER :: 35065-27-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C12-H4-Cl6

MOLECULAR WEIGHT :: 360.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg/30D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 322 mg/kg/13W-C

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg/3D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 960 mg/kg/4W-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Metabolism (Intermediary) - porphyrin including bile pigments

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1470 mg/kg/21D-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3650 mg/kg/104W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 50 mg/kg

SEX/DURATION :: female 8-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 448 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 112 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 448 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - physical

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 120 mg/kg

SEX/DURATION :: female 1-6 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 78 mg/kg

SEX/DURATION :: female 5-21 day(s) after conception lactating female 22 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: female 13-21 day(s) after conception lactating female 24 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 271 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1080 mg/kg

SEX/DURATION :: female 45-62 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

TYPE OF TEST :: DNA adduct

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 36400 ug/kg/5D

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 27,99,1979

Symbol	GHS08, GHS09
Signal Word	Warning
Hazard Statements	H373-H410
Precautionary Statements	P273-P391-P501
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	F: Flammable;Xi: Irritant;N: Dangerous for the environment;Xn: Harmful;
Risk Phrases	R11
Safety Phrases	16-26-33-36-61-60-35-62-29-9
RIDADR	UN 2315
Packaging Group	II
Hazard Class	9
HS Code	2903999090

Precursor 7
CAS#:108-86-1 Bromobenzene CAS#:95-94-3 1,2,4,5-Tetrach... CAS#:7145-82-6 Benzene,1,2,4-t... CAS#:35065-29-3 2,2',3,4,4',5,5'-PCB
CAS#:636-30-6 2,4,5-Trichloro... CAS#:120-82-1 1,2,4-Trichloro... CAS#:15721-02-5 2,2',5,5'-Tetra...
DownStream 10
CAS#:35694-08-7 OCTACHLOROBIPHENYL CAS#:51207-31-9 2,3,7,8-Tetrach... CAS#:92-52-4 Biphenyl CAS#:92-51-3 Bicyclohexane
CAS#:771-98-2 1-phenylcyclohe... CAS#:827-52-1 Cyclohexylbenzene CAS#:2051-60-7 pcb 1 CAS#:15862-07-4 2,4,5-Trichloro...
CAS#:33284-50-3 PCB 7 CAS#:70362-47-9 2,2',4,5-tetrac...

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Cross-omics gene and protein expression profiling in juvenile female mice highlights disruption of calcium and zinc signalling in the brain following dietary exposure to CB-153, BDE-47, HBCD or TCDD.

Toxicology 321 , 1-12, (2014)

The present study assessed if eating a diet of fish, spiked with persistent organic pollutants (POPs), affects gene and protein expression in the maturing mouse brain. Juvenile female Balb/c mice (22 ...

Associations of accumulated exposure to persistent organic pollutants with serum lipids and obesity in an adult cohort from Southern Spain.

Environ. Pollut. 195 , 9-15, (2014)

The aim of this research was to study the association of the accumulated human exposure to persistent organic pollutants with serum lipid levels and obesity, in a cohort of 298 adults. In the multivar...

Temporal dynamics of circulating persistent organic pollutants in a fasting seabird under different environmental conditions.

Environ. Sci. Technol. 46(18) , 10287-94, (2012)

Temporal dynamics of persistent organic pollutants (POPs) were examined in fasting common eider (Somateria mollissima) females in one subarctic (68° N; over 5 years) and one high arctic colony (78° N;...

2,2',4,4',5,5'-heptachlorobiphenyl

PCB 153

2,2',3,3',5,6'-HEXACHLOROBIPHENYL

HCBP

biphenyl, 2,2’,4,4’,5,5’-hexachloro-

CB-153

2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl

2,2',4,4',5,5'-PCB

1,1'-Biphenyl,2,2',4,4',5,5'-hexachloro

2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl (9CI)

PCB-153

Biphenyl, 2,2',4,4',5,5'-hexachloro-

2,2',4,4',5,5'-Hexachlorobiphenyl

1,1'-Biphenyl, 2,2',4,4',5,5'-hexachloro-

1,2,4-trichloro-5-(2,4,5-trichlorophenyl)benzene

2,4,5,2',4',5'-Hexachlorobiphenyl

2,2',4,4',5,5'-hexachloromobiphenyl

2,2′,4,4′,5,5′-Hexachlorobiphenyl

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PCB-153
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: PCB-153
Price: ￥1228.0/10mg
Purity: 96.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Pcb153
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,2',4,4',5,5'-HEXACHLOROBIPHENYL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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PCB-153

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MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Precursor & DownStream

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