Escin IIb

Modify Date: 2024-01-05 20:15:13

Escin IIb structure	Common Name	Escin IIb
	CAS Number	158800-83-0	Molecular Weight	1101.231
	Density	1.5±0.1 g/cm3	Boiling Point	1111.9±65.0 °C at 760 mmHg
	Molecular Formula	C₅₄H₈₄O₂₃	Melting Point	N/A
	MSDS	N/A	Flash Point	305.5±27.8 °C

Use of Escin IIb

Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals[1]. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions[2].

Name	06035642G6
Synonym	More Synonyms

Description	Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals[1]. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Escins Ia, Ib, IIa, and IIb (50-200 mg/kg) inhibit the increase of vascular permeability induced by both acetic acid in mice and histamine in rats. Escins Ib, IIa, and IIb (50-200 mg/kg) also inhibit that induced by serotonin in rats, but escin Ia didn't. Escins Ia, Ib, IIa, and IIb (200 mg/kg) inhibit the hind paw edema induced by carrageenin at the first phase in rats. Escin Ia (200 mg/kg) and escins Ib, IIa, and IIb (50-200 mg/kg) inhibit the scratching behavior induced by compound 48/80 in mice, but escin Ia was weakest[1]. Escin IIb (10-50 mg/kg; p.o.) potently inhibits ethanol-induced gastric mucosal lesions[2]. Animal Model: Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)[2] Dosage: P.o. Administration: 10-50 mg/kg Result: Showed a potent protective effect against ethanol-induced gastric lesions in rats.
References	[1]. Matsuda H, et al. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol Pharm Bull. 1997;20(10):1092-1095. [2]. Matsuda H, et al. Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats. Eur J Pharmacol. 1999;373(1):63-70.

Density	1.5±0.1 g/cm3
Boiling Point	1111.9±65.0 °C at 760 mmHg
Molecular Formula	C₅₄H₈₄O₂₃
Molecular Weight	1101.231
Flash Point	305.5±27.8 °C
Exact Mass	1100.540283
LogP	4.87
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.624

(3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2Z)-2-methyl-2-butenoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->4)-[β-D-xylopyranosyl-(1->2)]-β-D-glucopyranosiduronic 
acid

2-Butenoic acid, 2-methyl-, (3β,16α,21β,22α)-22-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->4)-O-[β-D-xylopyranosyl-(1->2)]-β-D-glucopyranuronosyl]oxy]-16,24,28-trihydroxyolean-12- 
en-21-yl ester, (2Z)-

(3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2Z)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->4)-[β-D-xylopyranosyl-(1->2)]-β-D-glucopyranosiduronic acid

06035642G6

MFCD10566615

2-butenoic acid, 2-methyl-, (3β,16α,21β,22α)-22-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->4)-O-[β-D-xylopyranosyl-(1->2)]-β-D-glucopyranuronosyl]oxy]-16,24,28-trihydroxyolean-12-en-21-yl ester, (2Z)-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Escin IIb
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Escin IIb
Price: ￥1768.0/10mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Get all suppliers and price by the below link:

Escin IIb suppliers

Escin IIb price

Escin IIb

Use of Escin IIb

Names

Escin IIb Biological Activity

Chemical & Physical Properties

Synonyms