N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide

Modify Date: 2024-01-02 20:42:51

N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide Structure
N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide structure
 Common Name N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide
CAS Number 15883-20-2 Molecular Weight 232.321
Density 1.1±0.1 g/cm3 Boiling Point 392.3±42.0 °C at 760 mmHg
Molecular Formula C14H20N2O Melting Point 114-117ºC
MSDS Chinese USA Flash Point 149.0±28.0 °C
Symbol GHS06
GHS06		 Signal Word Danger

 Use of N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide


Desbutylbupivacaine also known as N-Desbutyl Bupivacaine, it is a major metabolite of Bupivacaine.

 Names

Name N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 392.3±42.0 °C at 760 mmHg
Melting Point 114-117ºC
Molecular Formula C14H20N2O
Molecular Weight 232.321
Flash Point 149.0±28.0 °C
Exact Mass 232.157562
PSA 41.13000
LogP 2.29
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.567
Storage condition -20°C Freezer

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM6076000
CHEMICAL NAME :
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-
CAS REGISTRY NUMBER :
15883-20-2
BEILSTEIN REFERENCE NO. :
0206391
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H20-N2-O
MOLECULAR WEIGHT :
232.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CEXPB9 Clinical and Experimental Pharmacology and Physiology. (Blackwell Scientific Publications, (Australia) Pty Ltd., 107 Barry St., Carlton, Vic. 3053, Australia) V.1- 1974- Volume(issue)/page/year: 21,997,1994
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
45 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0155176

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements Missing Phrase - N15.00950417
Hazard Codes Xi: Irritant;
Risk Phrases 25
Safety Phrases 45
RIDADR UN 2811 6.1 / PGIII
RTECS TM6076000
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles25

More Articles
Kinetics of bupivacaine after clonidine pretreatment in mice.

Can. J. Anaesth. 42(5 Pt 1) , 434-7, (1995)

Previous studies have reported that clonidine pretreatment causes an increase in the local anaesthetic activity of bupivacaine. This study was designed to document possible changes in the pharmacokine...

Population pharmacokinetic analysis of ropivacaine and its metabolite 2',6'-pipecoloxylidide from pooled data in neonates, infants, and children.

Br. J. Anaesth. 107(3) , 409-24, (2011)

The aim was to characterize ropivacaine and 2',6'-pipecoloxylidide (PPX) pharmacokinetics and factors affecting them in paediatric anaesthesia.Population pharmacokinetics of ropivacaine and its active...

Bupivacaine kinetics during hyperthermia in rats.

Can. J. Anaesth. 41(3) , 253-6, (1994)

The aim of this study was to document possible alterations of bupivacaine pharmacokinetic behaviour in rats during hyperthermia. Two groups of Wistar AF IO PS male rats (Group A = normothermic control...

 Synonyms

N-(2',6'- Dinethylphenyl)-2-piperidinecarboxamide HCL
UNII:NF8RN1V7VM
Mepivacaine impurity B
Desbutylbupivacaine
(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide,Desbutylbupivacaine
N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide
N-Desbutyl Bupivacaine
MFCD08458869
2',6'-Pipecoloxylidide
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-
N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
N-(2',6'-Dimethylphenyl)-2-piperidinecarboxamide
(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
N-(2,6-DIMETHYLPHENYL ) -PIPERIDINE-2-CARBOXYLIC AMIDE
Bupivacaine Impurity 4
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Chemsrc provides CAS#:15883-20-2 MSDS, density, melting point, boiling point, structure, etc. Its name is N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide>> amp version: N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide

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