MPDC

Modify Date: 2025-08-25 14:43:17

MPDC Structure
MPDC structure
Common Name MPDC
CAS Number 159262-32-5 Molecular Weight 171.15
Density 1.6±0.1 g/cm3 Boiling Point 381.2±42.0 °C at 760 mmHg
Molecular Formula C7H9NO4 Melting Point N/A
MSDS N/A Flash Point 184.4±27.9 °C

 Use of MPDC


MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes[1].

 Names

Name (1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Synonym More Synonyms

 MPDC Biological Activity

Description MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes[1].
Related Catalog
Target

Glutamate transporter[1].

References

[1]. Bridges RJ, et al. A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate. Neurosci Lett. 1994 Jun 20;174(2):193-7.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 381.2±42.0 °C at 760 mmHg
Molecular Formula C7H9NO4
Molecular Weight 171.15
Flash Point 184.4±27.9 °C
Exact Mass 171.053162
LogP -1.43
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.594
InChIKey UNNFLFDQCHJXPI-QTBDOELSSA-N
SMILES O=C(O)C1NCC2C(C(=O)O)C12

 Safety Information

Hazard Codes Xi

 MPDCBioassay

View more

Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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 Synonyms

(1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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