MPDC

• 常用名: MPDC
• 英文名: MPDC
• CAS号: 159262-32-5
• 分子量: 171.15
• 密度: 1.6±0.1 g/cm3
• 沸点: 381.2±42.0 °C at 760 mmHg
• 分子式: C₇H₉NO₄
• 熔点: N/A
• 闪点: 184.4±27.9 °C

MPDC用途

MPDC 是竞争性的、前脑突触体中的、Na+依赖的、高亲和力的谷氨酸转运体抑制剂。

MPDC名称

• 中文名: MPDC
• 英文名: (1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid

MPDC生物活性

• 描述: MPDC 是竞争性的、前脑突触体中的、Na+依赖的、高亲和力的谷氨酸转运体抑制剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> GLYT
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> GLYT
• 靶点实验:

  Glutamate transporter[1].

• 参考文献:

  [1]. Bridges RJ, et al. A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate. Neurosci Lett. 1994 Jun 20;174(2):193-7.

MPDC物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 381.2±42.0 °C at 760 mmHg
• 分子式: C₇H₉NO₄
• 分子量: 171.15
• 闪点: 184.4±27.9 °C
• 精确质量: 171.053162
• LogP: -1.43
• InChIKey: UNNFLFDQCHJXPI-QTBDOELSSA-N
• SMILES: O=C(O)C1NCC2C(C(=O)O)C12
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 2-8°C，干燥，密封

MPDC安全信息

• 危害码 (欧洲): Xi

MPDC靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E... 来源：NCGC External Id：epac2-activator-v2

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4... 来源：NCGC External Id：epac2-inhibitor-v2

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

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MPDC英文别名

• (1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid