MSN-125

Modify Date: 2024-01-08 19:50:18

MSN-125 structure	Common Name	MSN-125
	CAS Number	1592908-16-1	Molecular Weight	688.619
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₃₈BrN₃O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MSN-125

MSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM; potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity.

Name	MSN-125

Description	MSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM; potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity.
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Bax Bak
In Vitro	MSN-125 inhibits tBid/Bax-mediated MOMP in a concentration-dependent manner[1].
References	[1]. Niu X, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chem Biol. 2017 Apr 20;24(4):493-506.e5.

Molecular Formula	C₃₆H₃₈BrN₃O₆
Molecular Weight	688.619

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: MSN-125
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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