Wikstrol A

Modify Date: 2024-01-18 16:54:56

Wikstrol A Structure
Wikstrol A structure
Common Name Wikstrol A
CAS Number 159736-35-3 Molecular Weight 542.490
Density 1.6±0.1 g/cm3 Boiling Point 925.3±65.0 °C at 760 mmHg
Molecular Formula C30H22O10 Melting Point N/A
MSDS N/A Flash Point 311.8±27.8 °C

 Use of Wikstrol A


Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].

 Names

Name 3',5,5',7,7'-Pentahydroxy-2,2'-bis(4-hydroxyphenyl)-3',4'-dihydro-2'H,4H-3,8'-bichromen-4-one
Synonym More Synonyms

 Wikstrol A Biological Activity

Description Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].
Related Catalog
Target

HIV-1:67.8 (IC50)

References

[1]. Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 925.3±65.0 °C at 760 mmHg
Molecular Formula C30H22O10
Molecular Weight 542.490
Flash Point 311.8±27.8 °C
Exact Mass 542.121277
LogP 4.63
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.786

 Synonyms

[3,8'-Bi-4H-1-benzopyran]-4-one, 2',3'-dihydro-3',5,5',7,7'-pentahydroxy-2,2'-bis(4-hydroxyphenyl)-
3',5,5',7,7'-Pentahydroxy-2,2'-bis(4-hydroxyphenyl)-3',4'-dihydro-2'H,4H-3,8'-bichromen-4-one