T-448

Modify Date: 2024-07-18 18:14:42

T-448 Structure
T-448 structure
 Common Name T-448
CAS Number 1597426-53-3 Molecular Weight 772.94
Density N/A Boiling Point N/A
Molecular Formula C38H44N8O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T-448


T-448 is a specific and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons[1].

 Names

Name T-448

 T-448 Biological Activity

Description T-448 is a specific and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons[1].
Related Catalog
Target

IC50: 22 nM (LSD1)[1].

References

[1]. Matsuda S, et al. T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice. Neuropsychopharmacology. 2018 Dec 22.

 Chemical & Physical Properties

Molecular Formula C38H44N8O6S2
Molecular Weight 772.94
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Chemsrc provides T-448(CAS#:1597426-53-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of T-448 are included as well.>> amp version: T-448

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