Ulipristal

Modify Date: 2024-01-02 12:49:51

Ulipristal Structure
Ulipristal structure
Common Name Ulipristal
CAS Number 159811-51-5 Molecular Weight 433.582
Density 1.2±0.1 g/cm3 Boiling Point 638.5±55.0 °C at 760 mmHg
Molecular Formula C28H35NO3 Melting Point 183.5-184.5ºC /Losartan/
MSDS N/A Flash Point 340.0±31.5 °C

 Use of Ulipristal


Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].

 Names

Name (8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Synonym More Synonyms

 Ulipristal Biological Activity

Description Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].
Related Catalog
In Vivo Ulipristal (CDB 3236) may suppress the growth of uterine leiomyomatosis. By inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception[1].
References

[1]. LIANA PLES, et al. Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate. REV.CHIM.(Bucharest).

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 638.5±55.0 °C at 760 mmHg
Melting Point 183.5-184.5ºC /Losartan/
Molecular Formula C28H35NO3
Molecular Weight 433.582
Flash Point 340.0±31.5 °C
Exact Mass 433.261688
PSA 57.61000
LogP 3.86
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.613

 Synthetic Route

 Synonyms

6J5J15Q2X8
Deacetyl CDB 2914
Ulipristal [USAN:INN:BAN]
(11β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione
Ulipristal (USAN/INN)
Ulipristal,11beta-[4-(N,N-diMethylaMino)-phenyl]-17alpha-hydroxy-19-norpregna-4,9-diene-3,20-dione
Estra-4,9-dien-3-one, 17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-, (11β,17α)-
Ulipristal
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Price: ¥1650/10 mM * 1 mL in DMSO

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