159811-51-5

159811-51-5 structure

Name: Ulipristal
Chemical Name: (8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
CAS Number: 159811-51-5
Molecular Formula: C₂₈H₃₅NO₃
Molecular Weight: 433.582
Catalog: Biochemical Inhibitor Endocrinology & Hormones Estrogen/progestogen Receptor regulator
Create Date: 2018-07-25 15:54:38
Modify Date: 2024-01-02 12:49:51
Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].

Name	(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Synonyms	6J5J15Q2X8 Deacetyl CDB 2914 Ulipristal [USAN:INN:BAN] (11β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione Ulipristal (USAN/INN) Ulipristal,11beta-[4-(N,N-diMethylaMino)-phenyl]-17alpha-hydroxy-19-norpregna-4,9-diene-3,20-dione Estra-4,9-dien-3-one, 17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-, (11β,17α)- Ulipristal

Description	Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].
Related Catalog	Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Cancer Research Areas >> Endocrinology
In Vivo	Ulipristal (CDB 3236) may suppress the growth of uterine leiomyomatosis. By inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception[1].
References	[1]. LIANA PLES, et al. Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate. REV.CHIM.(Bucharest).