AZD3264

Modify Date: 2024-01-09 22:22:55

AZD3264 Structure
AZD3264 structure
Common Name AZD3264
CAS Number 1609281-86-8 Molecular Weight 441.503
Density 1.4±0.1 g/cm3 Boiling Point 614.2±55.0 °C at 760 mmHg
Molecular Formula C21H23N5O4S Melting Point N/A
MSDS N/A Flash Point 325.2±31.5 °C

 Use of AZD3264


AZD3264 is a selective IkB-kinase IKK2 inhibitor.

 Names

Name azd3264
Synonym More Synonyms

 AZD3264 Biological Activity

Description AZD3264 is a selective IkB-kinase IKK2 inhibitor.
Related Catalog
Target

IKK2

In Vivo AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma[1].
References

[1]. Andiappan Murugan, et al. Exploiting the Differential Reactivities of Halogen Atoms: Development of a Scalable Route to IKK2 Inhibitor AZD3264. Org Process Res Dev. 2014 Apr 29;18(5): 646-651.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 614.2±55.0 °C at 760 mmHg
Molecular Formula C21H23N5O4S
Molecular Weight 441.503
Flash Point 325.2±31.5 °C
Exact Mass 441.147064
LogP 2.08
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.653
Storage condition -20℃

 Synonyms

2-(Carbamoylamino)-5-{4-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3S)-3-pyrrolidinyloxy]phenyl}-3-thiophenecarboxamide
3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-[4-(3,5-dimethyl-4-isoxazolyl)-2-[(3S)-3-pyrrolidinyloxy]phenyl]-