LX2761

Modify Date: 2024-01-03 16:06:32

LX2761 Structure
LX2761 structure
Common Name LX2761
CAS Number 1610954-97-6 Molecular Weight 601.31
Density N/A Boiling Point N/A
Molecular Formula C32H47N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LX2761


LX2761 is chemically stable and potent inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 in vitro with IC50s of 2.2 nM and 2.7nM for hSGLT1 and hSGLT2, but displays specific SGLT1 inhibition in the gastrointestinal (GI) tract[1].

 Names

Name LX-2761

 LX2761 Biological Activity

Description LX2761 is chemically stable and potent inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 in vitro with IC50s of 2.2 nM and 2.7nM for hSGLT1 and hSGLT2, but displays specific SGLT1 inhibition in the gastrointestinal (GI) tract[1].
Related Catalog
Target

IC50: 2.2 nM (hSGLT1), 2.7nM (hSGLT2)[1]

References

[1]. Goodwin NC, et al. Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restrictedto the Intestinal Lumen, for the Treatment of Diabetes. J Med Chem. 2017 Jan 26;60(2):710-721.

 Chemical & Physical Properties

Molecular Formula C32H47N3O6S
Molecular Weight 601.31
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: LX-2761
  • Price: $850.0/100mg $1500.0/250mg $2900.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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