Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt

Modify Date: 2025-08-25 18:33:41

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt structure	Common Name	Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt
	CAS Number	161552-03-0	Molecular Weight	603.670
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₇H₄₁N₉O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Sequence: Cyclo(Arg-Gly-Asp-Phe-Lys).

Name	2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
Synonym	More Synonyms

Description	Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Sequence: Cyclo(Arg-Gly-Asp-Phe-Lys).
Related Catalog	Signaling Pathways >> Cytoskeleton >> Integrin Research Areas >> Cancer Peptides Peptides
Target	IC50: 0.94 nM (αvβ3 integrin)[1].
In Vitro	Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with a IC50 of 0.94 nM[1]. [(66)Ga]DOTA-E-[c(RGDfK)]2 can be prepared with high radiochemical purity (>97%), specific activity (36-67GBq/μM), in vitro stability, and moderate protein binding. MicroPET imaging up to 24 post-injection showed contrasting tumors reflecting αvβ3-targeted tracer accumulation[2].
References	[1]. Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95. [2]. Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.

Density	1.5±0.1 g/cm3
Molecular Formula	C₂₇H₄₁N₉O₇
Molecular Weight	603.670
Exact Mass	603.312866
PSA	288.17000
LogP	-3.10
Index of Refraction	1.666
Storage condition	-20°C

N/A structure

N/A

CAS#:1035105-00-0

~%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt Structure

Cyclo(-Arg-Gly-...

CAS#:161552-03-0

Literature: Petersen, Svea; Alonso, Jose Maria; Specht, Alexandre; Duodu, Portia; Goeldner, Maurice; Del Campo, Aranzazu Angewandte Chemie - International Edition, 2008 , vol. 47, # 17 p. 3192 - 3195

FMOC-ASP(OTBU)-OH structure

FMOC-ASP(OTBU)-OH

CAS#:71989-14-5

~%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt Structure

Cyclo(-Arg-Gly-...

CAS#:161552-03-0

Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790

Fmoc-D-Phe-OH structure

Fmoc-D-Phe-OH

CAS#:86123-10-6

~%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt Structure

Cyclo(-Arg-Gly-...

CAS#:161552-03-0

Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790

Fmoc-Lys(Alloc)-OH structure

Fmoc-Lys(Alloc)-OH

CAS#:146982-27-6

~%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt Structure

Cyclo(-Arg-Gly-...

CAS#:161552-03-0

Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790

FMOC-ASP(OTBU)-OH structure

FMOC-ASP(OTBU)-OH

CAS#:71989-14-5

Fmoc-D-Phe-OH structure

Fmoc-D-Phe-OH

CAS#:86123-10-6

Alloc-Lys(Fmoc)-OH structure

Alloc-Lys(Fmoc)-OH

CAS#:186350-56-1

~%

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt Structure

Cyclo(-Arg-Gly-...

CAS#:161552-03-0

Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790

Cyclo (-RGDfK)

c(D-Phe-Lys-Arg-Gly-Asp)

A8164

Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl)

cyclo-[Arg-Gly-Asp-D-Phe-Lys]

Cyclo[L-α-aspartyl-D-phenylalanyl-L-lysyl-N-(diaminomethylene)-L-ornithylglycyl]

cyclic-RGD peptide

cyclo[RGD-{D-F}-K]

cyclo(RGDfK)

Cyclo-RGDfK

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclo(-Arg-Gly-Asp-D-Phe-Lys)
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Cyclo(-RGDfK)
Price: $500.0/100mg $950.0/250mg $1800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: cyclo(-RGDfK)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Nanjing Peptide Biotech Ltd
China
Product Name: Cyclo(RGDfK)
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Delivery: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Get all suppliers and price by the below link:

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt suppliers

Price: $185/10mM*1mLinDMSO

Reference only. check more Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt price