c-Fms-IN-9

Modify Date: 2024-01-13 23:13:00

c-Fms-IN-9 Structure
c-Fms-IN-9 structure
Common Name c-Fms-IN-9
CAS Number 1628574-50-4 Molecular Weight 405.45
Density N/A Boiling Point N/A
Molecular Formula C21H23N7O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of c-Fms-IN-9


c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

 Names

Name c-Fms-IN-9

 c-Fms-IN-9 Biological Activity

Description c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].
Related Catalog
Target

c-FMS[1]

In Vitro c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].
References

[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

 Chemical & Physical Properties

Molecular Formula C21H23N7O2
Molecular Weight 405.45