p Tolylmaleimide

Modify Date: 2024-01-12 16:24:05

p Tolylmaleimide Structure
p Tolylmaleimide structure
Common Name p Tolylmaleimide
CAS Number 1631-28-3 Molecular Weight 187.19500
Density 1.277g/cm3 Boiling Point 333.2ºC at 760mmHg
Molecular Formula C11H9NO2 Melting Point N/A
MSDS N/A Flash Point 154.2ºC

 Use of p Tolylmaleimide


p-Tolylmaleimide is a water channel inhibitor which binds to aquaporin Z (AqpZ).

 Names

Name 1-(4-methylphenyl)-1h-pyrrole-2,5-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.277g/cm3
Boiling Point 333.2ºC at 760mmHg
Molecular Formula C11H9NO2
Molecular Weight 187.19500
Flash Point 154.2ºC
Exact Mass 187.06300
PSA 37.38000
LogP 1.48940
Vapour Pressure 0.000139mmHg at 25°C
Index of Refraction 1.615

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ON6475000
CHEMICAL NAME :
Maleimide, N-p-tolyl-
CAS REGISTRY NUMBER :
1631-28-3
BEILSTEIN REFERENCE NO. :
0131320
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H9-N-O2
MOLECULAR WEIGHT :
187.21
WISWESSER LINE NOTATION :
T5VNVJ BR D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,22,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

 Safety Information

Hazard Codes Xi: Irritant;
HS Code 2925190090

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

n-p-tolyl-maleimid
N-4-Tolylmaleimide
Maleimide,N-p-Tolyl
MFCD00022581
p-Tolylmaleimide
IT 510