Elobixibat hydrate

Modify Date: 2024-01-04 20:29:33

Elobixibat hydrate Structure
Elobixibat hydrate structure
Common Name Elobixibat hydrate
CAS Number 1633824-78-8 Molecular Weight 713.90
Density N/A Boiling Point N/A
Molecular Formula C36H47N3O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Elobixibat hydrate


Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research[1].

 Names

Name Elobixibat hydrate

 Elobixibat hydrate Biological Activity

Description Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research[1].
Related Catalog
Target

IC50: 0.53±0.17 nM (human IBAT), 0.13±0.03 nM (mouse IBAT), 5.8±1.6 nM (canine IBAT)[1].

References

[1]. Wong BS, et al. Elobixibat for the treatment of constipation. Expert Opin Investig Drugs. 2013 Feb; 22(2):277-84.

 Chemical & Physical Properties

Molecular Formula C36H47N3O8S2
Molecular Weight 713.90
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Elobixibat hydrate suppliers

Elobixibat hydrate price

Related Compounds: More...
Elobixibat
439087-18-0
aniline,hydrate
179938-55-7
dodecylmercury,hydrate
56986-39-1
aluminum hydrate
20768-67-6
anthracene,hydrate
188974-01-8
uranium,hydrate
380612-88-4
MOEXIPRILAT HYDRATE
82586-57-0
2-[bis[2-[carboxylatomethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetate,dysprosium(3+),hexahydrate
140224-06-2
methylsulfanylmethane,hydrate
58328-83-9
Ethyl 2-{[(4-methyl-1,2,3-thiadiazol-5-yl)carbonyl]amino}-1,3-benzothiazole-6-carboxylate
898635-82-0
N-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamide
898605-34-0
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-(4-chlorophenyl)-4-oxo-1,4-dihydropyridazine-3-carboxamide
898605-40-8
4-methyl-N-{3-[(2-phenylethyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl}-1,2,3-thiadiazole-5-carboxamide
898605-41-9
N-{[5-(4-chlorophenyl)furan-2-yl]methyl}-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide
879594-96-4
(2E)-N-{[5-(4-chlorophenyl)furan-2-yl]methyl}-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(4-methoxyphenyl)prop-2-enamide
898605-45-3
(2E)-N-{[5-(4-chlorophenyl)furan-2-yl]methyl}-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-phenylprop-2-enamide
898605-47-5
N-{[5-(4-chlorophenyl)furan-2-yl]methyl}-N-(1,1-dioxidotetrahydrothiophen-3-yl)-4-methoxybenzamide
879762-73-9
1-(4-methoxyphenyl)-4-oxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1,4-dihydropyridazine-3-carboxamide
898605-50-0
1-(3-chlorophenyl)-4-oxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1,4-dihydropyridazine-3-carboxamide
898605-51-1