Elobixibat
Modify Date: 2024-01-08 20:00:22
Elobixibat structure
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Common Name | Elobixibat | ||
|---|---|---|---|---|
| CAS Number | 439087-18-0 | Molecular Weight | 695.88800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H45N3O7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ElobixibatElobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. |
| Name | 2-[[(2R)-2-[[2-[(3,3-dibutyl-7-methylsulfanyl-1,1-dioxo-5-phenyl-2,4-dihydro-1λ6,5-benzothiazepin-8-yl)oxy]acetyl]amino]-2-phenylacetyl]amino]acetic acid |
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| Synonym | More Synonyms |
| Description | Elobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. |
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| Related Catalog | |
| Target |
IC50: 0.53±0.17 nM (human IBAT), 0.13±0.03 nM (mouse IBAT), 5.8±1.6 nM (canine IBAT)[1]. |
| References |
| Molecular Formula | C36H45N3O7S2 |
|---|---|
| Molecular Weight | 695.88800 |
| Exact Mass | 695.27000 |
| PSA | 182.77000 |
| LogP | 8.96420 |
| Glycine,(2R)-N-(2-((3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl)oxy)acetyl)-2-phenylglycyl |
| UNII-865UEK4EJC |
| Elobixibat |
| AZD-7806 |
| Elobixibat [INN] |