trans-Zeatin

Modify Date: 2024-01-05 00:29:35

trans-Zeatin Structure
trans-Zeatin structure
Common Name trans-Zeatin
CAS Number 1637-39-4 Molecular Weight 219.243
Density 1.4±0.1 g/cm3 Boiling Point 395.0±52.0 °C at 760 mmHg
Molecular Formula C10H13N5O Melting Point 207 °C
MSDS Chinese USA Flash Point 192.7±30.7 °C

 Use of trans-Zeatin


trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.

 Names

Name trans-zeatin
Synonym More Synonyms

 trans-Zeatin Biological Activity

Description trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
Related Catalog
Target

MEK

ERK

In Vitro trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division[1]. trans-Zeatin (20, 40 or 80 μM) inhibits UV-induced MEK/ERK activation, upregulates AQP3 in a time- and dose-dependent manner, and attenuates UV induced loss of AQP3 in keratinocytes (HaCaT cells). UV-induced AQP3 downregulation is blocked by MEK/ERK inhibitors. Trans-Zeatin (80 μM) attenuates UV-induced downregulation of wound healing and water permeability in HaCaT cells[2].
References

[1]. Li Q, et al. Endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey. Environ Sci Pollut Res Int. 2016 Dec;23(23):23422-23435. Epub 2016 Sep 9.

[2]. Ji C, et al. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int J Mol Med. 2010 Aug;26(2):257-63.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 395.0±52.0 °C at 760 mmHg
Melting Point 207 °C
Molecular Formula C10H13N5O
Molecular Weight 219.243
Flash Point 192.7±30.7 °C
Exact Mass 219.112015
PSA 86.72000
LogP -1.02
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.684
Storage condition −20°C
Water Solubility H2O: soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EM9506000
CHEMICAL NAME :
2-Buten-1-ol, 2-methyl-4-(purin-6-ylamino)-, (E)-
CAS REGISTRY NUMBER :
1637-39-4
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H13-N5-O
MOLECULAR WEIGHT :
219.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Leukocyte
DOSE/DURATION :
100 umol/L
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,29,1976

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS EM9506000

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 Synonyms

(2z)-2-methyl-4-(9h-purin-6-ylamino)but-2-en-1-ol
2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (2E)-
cis-zeatin
trans-Zeatin (synthetic)
(2E)-2-Methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol
2-Buten-1-ol, 2-methyl-4-(3H-purin-6-ylamino)-, (2Z)-
(E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol
oxyenadenine
(2E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol
ZEATIN TRANS ISOMER
(2Z)-2-Methyl-4-(3H-purin-6-ylamino)-2-buten-1-ol
2-Buten-1-ol, 2-methyl-4-(3H-purin-6-ylamino)-, (2E)-
6-(4-Hydroxy-3-methyl-2-butenylamino)purine
(E)-zeatin
(2E)-2-Methyl-4-(3H-purin-6-ylamino)-2-buten-1-ol
MFCD00213654
(2E)-2-Methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol
trans-Zeatin
(2E)-2-Methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol
2-Buten-1-ol, 2-methyl-4-(purin-6-ylamino)-, (E)-
N6-(4-Hydroxy-3-methyl-2-buten-1-yl)adenine
Zeatin
6-(4-Hydroxy-3-methylbut-2-enylamino)purine (N6-(4-Hydroxy-3-methyl-2-buten-1-yl)adenine
Zeatine
(2Z)-2-Methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol
TRANS ISOMER-ZEATIN
ZEATINRESEARCH GRADE
2-Buten-1-ol, 2-methyl-4-(7H-purin-6-ylamino)-, (2Z)-
6-(4-Hydroxy-3-methylbut-2-enylamino)purine
2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (E)-
ZEATIN,CRYSTALLIZED
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