BDM-2
Modify Date: 2024-01-17 19:46:34
BDM-2 structure
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Common Name | BDM-2 | ||
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| CAS Number | 1643876-33-8 | Molecular Weight | 394.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H30O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BDM-2BDM-2 is an IN-LEDGF allosteric inhibitor (INLAI) of HIV-1 integrase (IN refers to integrase) (IC50=47 nM) with potent anti-Retroviral (ARV) activity. BDM-2 shows IN multimerization activation effect with an AC50 value of 20 nM. BDM-2 blocks the interaction between the catalytic core domain of IN (IN-CCD) and the Integrase binding domain of LEDGF/p75 (IBD), with an IC50 value of 0.15 μM. BDM-2 exhibits highly selective and favorable cytotoxicity[1]. |
| Name | BDM-2 |
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| Description | BDM-2 is an IN-LEDGF allosteric inhibitor (INLAI) of HIV-1 integrase (IN refers to integrase) (IC50=47 nM) with potent anti-Retroviral (ARV) activity. BDM-2 shows IN multimerization activation effect with an AC50 value of 20 nM. BDM-2 blocks the interaction between the catalytic core domain of IN (IN-CCD) and the Integrase binding domain of LEDGF/p75 (IBD), with an IC50 value of 0.15 μM. BDM-2 exhibits highly selective and favorable cytotoxicity[1]. |
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| Related Catalog | |
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| Molecular Formula | C25H30O4 |
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| Molecular Weight | 394.50 |