Epiblastin A

Modify Date: 2024-01-03 18:25:51

Epiblastin A Structure
Epiblastin A structure
Common Name Epiblastin A
CAS Number 16470-02-3 Molecular Weight 287.708
Density 1.6±0.1 g/cm3 Boiling Point 596.1±60.0 °C at 760 mmHg
Molecular Formula C12H10ClN7 Melting Point N/A
MSDS N/A Flash Point 314.3±32.9 °C

 Use of Epiblastin A


Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].

 Names

Name Epiblastin A
Synonym More Synonyms

 Epiblastin A Biological Activity

Description Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].
Related Catalog
References

[1]. Andrei Ursu, et al. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol. 2016 Apr 21;23(4):494-507.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 596.1±60.0 °C at 760 mmHg
Molecular Formula C12H10ClN7
Molecular Weight 287.708
Flash Point 314.3±32.9 °C
Exact Mass 287.068634
LogP 1.90
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.821
Storage condition -20°C

 Synonyms

MFCD02947161
6-(3-Chlorophenyl)-2,4,7-pteridinetriamine
6-(3-Chlorophenyl)pteridine-2,4,7-Triamine
2,4,7-Triamino-6-(m-chlorophenyl)-pteridine
2,4,7-Pteridinetriamine, 6-(3-chlorophenyl)-
Epiblastin A