O4I2
Modify Date: 2024-01-02 21:46:33
O4I2 structure
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Common Name | O4I2 | ||
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| CAS Number | 165682-93-9 | Molecular Weight | 282.746 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 408.1±51.0 °C at 760 mmHg | |
| Molecular Formula | C12H11ClN2O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 200.6±30.4 °C | |
Use of O4I2O4I2 is a potent Oct3/4 inducer in various human cell lines including human fibroblasts.Target: Oct3/4O4I2 activates Oct3/4 in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts. O4I2 activates also other pluripotencyassociatedgenes such as Lin28 and Nanog in a drug-like manner. O4I2 shows high activity in enforcing Oct3/4 expression. O4I2 activates Oct3/4 on the transcriptional and translational level in human fibroblasts. O4I2 promotes the expression of pluripotency-associated genes as analyzed by qRT-PCR in human neonatal foreskin fibroblasts (HFFs). O4I2 markedly stimulates Oct3/4 even at 5 μM after 72 h treatment on the translational level. |
| Name | ethyl 2-(4-chloroanilino)-1,3-thiazole-4-carboxylate |
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| Synonym | More Synonyms |
| Description | O4I2 is a potent Oct3/4 inducer in various human cell lines including human fibroblasts.Target: Oct3/4O4I2 activates Oct3/4 in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts. O4I2 activates also other pluripotencyassociatedgenes such as Lin28 and Nanog in a drug-like manner. O4I2 shows high activity in enforcing Oct3/4 expression. O4I2 activates Oct3/4 on the transcriptional and translational level in human fibroblasts. O4I2 promotes the expression of pluripotency-associated genes as analyzed by qRT-PCR in human neonatal foreskin fibroblasts (HFFs). O4I2 markedly stimulates Oct3/4 even at 5 μM after 72 h treatment on the translational level. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 408.1±51.0 °C at 760 mmHg |
| Molecular Formula | C12H11ClN2O2S |
| Molecular Weight | 282.746 |
| Flash Point | 200.6±30.4 °C |
| Exact Mass | 282.022980 |
| PSA | 79.46000 |
| LogP | 3.83 |
| Appearance of Characters | light yellow solid |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.637 |
| Storage condition | -20℃ |
| RIDADR | NONH for all modes of transport |
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| HS Code | 2934100090 |
| HS Code | 2934100090 |
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| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
| Ethyl 2-[(4-chlorophenyl)amino]-1,3-thiazole-4-carboxylate |
| ETHYL 2-(4-CHLOROPHENYLAMINO)-4-THIAZOLECARBOXYLATE |
| 4-Thiazolecarboxylic acid, 2-[(4-chlorophenyl)amino]-, ethyl ester |
| O4I2 |