NTE-122
Modify Date: 2025-09-13 09:04:54
NTE-122 structure
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Common Name | NTE-122 | ||
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| CAS Number | 166967-84-6 | Molecular Weight | 703.828 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H60Cl2N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NTE-122NTE-122 (dihydrochloride) is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with the IC50 in liver and aorta of cholesterol-fed rabbits of 7.6nM, 4.4nM and 9.6 nM, respectively, that plays an important role in atherosclerosis[1]. |
| Name | 1,1'-[trans-1,4-Cyclohexanediylbis(methylene)]bis{1-cyclohexyl-3-[4-(dimethylamino)phenyl]urea} dihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | NTE-122 (dihydrochloride) is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with the IC50 in liver and aorta of cholesterol-fed rabbits of 7.6nM, 4.4nM and 9.6 nM, respectively, that plays an important role in atherosclerosis[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C38H60Cl2N6O2 |
|---|---|
| Molecular Weight | 703.828 |
| Exact Mass | 702.415466 |
| InChIKey | SIHFCVXQGXGQQO-UHFFFAOYSA-N |
| SMILES | CN(C)c1ccc(NC(=O)N(CC2CCC(CN(C(=O)Nc3ccc(N(C)C)cc3)C3CCCCC3)CC2)C2CCCCC2)cc1 |
| 1,1'-[trans-1,4-Cyclohexanediylbis(methylene)]bis{1-cyclohexyl-3-[4-(dimethylamino)phenyl]urea} dihydrochloride |
| Urea, N,N''-[trans-1,4-cyclohexanediylbis(methylene)]bis[N-cyclohexyl-N'-[4-(dimethylamino)phenyl]-, hydrochloride (1:2) |