FR173657
Modify Date: 2024-01-31 09:43:48
FR173657 structure
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Common Name | FR173657 | ||
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| CAS Number | 167838-64-4 | Molecular Weight | 592.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H27Cl2N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FR173657FR173657 is an orally active bradykinin B2 receptor antagonist (IC50: 0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively). FR173657 (p.o.) inhibits BK-induced bronchoconstriction in guinea-pigs (ED50: 0.075 mg/kg). FR173657 (p.o.) also inhibits Carrageenin-induced paw oedema in mice (ED50: 6.8 mg/kg). FR173657 can be used for research of inflammatory disease[1]. |
| Name | FR173657 |
|---|
| Description | FR173657 is an orally active bradykinin B2 receptor antagonist (IC50: 0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively). FR173657 (p.o.) inhibits BK-induced bronchoconstriction in guinea-pigs (ED50: 0.075 mg/kg). FR173657 (p.o.) also inhibits Carrageenin-induced paw oedema in mice (ED50: 6.8 mg/kg). FR173657 can be used for research of inflammatory disease[1]. |
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| Related Catalog | |
| Target |
0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively[1] |
| References |
| Molecular Formula | C30H27Cl2N5O4 |
|---|---|
| Molecular Weight | 592.47 |