3-Hydroxymandelic Acid

Modify Date: 2024-01-02 12:01:00

3-Hydroxymandelic Acid Structure
3-Hydroxymandelic Acid structure
Common Name 3-Hydroxymandelic Acid
CAS Number 17119-15-2 Molecular Weight 168.14700
Density 1.48g/cm3 Boiling Point 424.3ºC at 760mmHg
Molecular Formula C8H8O4 Melting Point 128-132ºC
MSDS Chinese USA Flash Point 224.5ºC

 Use of 3-Hydroxymandelic Acid


3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist.

 Names

Name 3-hydroxymandelic acid
Synonym More Synonyms

 3-Hydroxymandelic Acid Biological Activity

Description 3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Phenylephrine, an alpha-receptor agonist is metabolized to m-hydroxyphenylglycol (MHPG) and m-hydroxymandelic acid (MHMA) in the human body[1]. It is probable that urinary MHMA originates from m-octopamine or m-synephrine (Phenylephrine) or both[1].
References

[1]. Gumbhir K, et al. Determination of m-hydroxymandelic acid, m-hydroxyphenylglycol and their conjugates in human plasma using liquid chromatography with electrochemical detection. J Pharm Biomed Anal. 1994 Jul;12(7):943-9.

[2]. Crowley JR, et al. Normal excretion of m-hydroxymandelic acid in hypertensive patients. Clin Chim Acta. 1981 Jan 22;109(2):125-31.

 Chemical & Physical Properties

Density 1.48g/cm3
Boiling Point 424.3ºC at 760mmHg
Melting Point 128-132ºC
Molecular Formula C8H8O4
Molecular Weight 168.14700
Flash Point 224.5ºC
Exact Mass 168.04200
PSA 77.76000
LogP 0.51020
Vapour Pressure 5.91E-08mmHg at 25°C
Index of Refraction 1.637

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918290000

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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 Synonyms

3-Hydroxy-mandelsaeure
3-Hydroxymandelic Acid
EINECS 241-182-3
M-hydroxymandelate
MFCD00042723
m-Hydroxymandelic acid
MHMA
3-Hydroxyphenylglycolic acid
2-hydroxy-2-(3-hydroxyphenyl)acetic acid
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