SMAP-29

Modify Date: 2025-08-27 09:51:47

SMAP-29 Structure
SMAP-29 structure
Common Name SMAP-29
CAS Number 172485-26-6 Molecular Weight 3256.02
Density N/A Boiling Point N/A
Molecular Formula C146H260N52O32 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SMAP-29


SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism[1][2].

 Names

Name SMAP-29

 SMAP-29 Biological Activity

Description SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism[1][2].
Related Catalog
Target

IC50: bacterial; fungal[1]

References

[1]. B Skerlavaj, et al. SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes. FEBS Lett. 1999 Dec 10;463(1-2):58-62.

[2]. Rachel C Anderson, et al.Antimicrobial activity and bacterial-membrane interaction of ovine-derived cathelicidins. Antimicrob Agents Chemother

 Chemical & Physical Properties

Molecular Formula C146H260N52O32
Molecular Weight 3256.02
InChIKey FCADNARZMFOBRZ-PJTASCKWSA-N
SMILES CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(N)CCCNC(=N)N)C(=O)NC(C)C(=O)NC(Cc1cnc[nH]1)C(=O)NCC(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(C)C(=O)NCC(=O)O)C(C)CC)C(C)CC)C(C)CC)C(C)C)C(C)O)C(C)C
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