ly 272015 hydrochloride

Modify Date: 2025-08-28 15:24:40

ly 272015 hydrochloride structure	Common Name	ly 272015 hydrochloride
	CAS Number	172895-15-7	Molecular Weight	372.88800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₅ClN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ly 272015 hydrochloride

LY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats[1][2].

Name	1-[(3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Synonym	More Synonyms

Description	LY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT2B Receptor
References	[1]. S W Watts, et al. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. Am J Physiol. 1999 Mar;276(3):H944-52. [2]. Kota Naito, et al. Signal Transduction Mechanism for Serotonin 5-HT2B Receptor-Mediated DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes. Biol Pharm Bull. 2016;39(1):121-9.

Molecular Formula	C₂₁H₂₅ClN₂O₂
Molecular Weight	372.88800
Exact Mass	372.16000
PSA	46.28000
LogP	5.05380
Storage condition	Store at +4°C

ly-272,015

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ly 272015 hydrochloride
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: LY-272015 hydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: LY 272015 HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

ly 272015 hydrochloride suppliers

ly 272015 hydrochloride price

ly 272015 hydrochloride

Use of ly 272015 hydrochloride

Names

ly 272015 hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.