Oxotremorine sesquifumarate
Modify Date: 2025-08-23 12:17:14
Oxotremorine sesquifumarate structure
|
Common Name | Oxotremorine sesquifumarate | ||
|---|---|---|---|---|
| CAS Number | 17360-35-9 | Molecular Weight | 760.78500 | |
| Density | N/A | Boiling Point | 373.9ºC at 760 mmHg | |
| Molecular Formula | C36H48N4O14 | Melting Point | 102-105ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 169.1ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of Oxotremorine sesquifumarateOxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2]. |
| Name | Oxotremorine sesquifumarate salt |
|---|---|
| Synonym | More Synonyms |
| Description | Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Oxotremorine (10.5 μM) produces a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1]. |
| In Vivo | In rats with sciatic nerve injuries, Oxotremorine (10, 5, 2 1 μg; 10 μL) i.t. dose-dependently suppresses the tactile hypersensitivity[2]. |
| References |
| Boiling Point | 373.9ºC at 760 mmHg |
|---|---|
| Melting Point | 102-105ºC(lit.) |
| Molecular Formula | C36H48N4O14 |
| Molecular Weight | 760.78500 |
| Flash Point | 169.1ºC |
| Exact Mass | 760.31700 |
| PSA | 270.90000 |
| LogP | 0.30300 |
| Vapour Pressure | 8.7E-06mmHg at 25°C |
| InChIKey | WLYYOFJEBGHKEC-VQYXCCSOSA-N |
| SMILES | O=C(O)C=CC(=O)O.O=C(O)C=CC(=O)O.O=C(O)C=CC(=O)O.O=C1CCCN1CC#CCN1CCCC1.O=C1CCCN1CC#CCN1CCCC1 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H310-H330 |
| Precautionary Statements | P260-P264-P280-P284-P302 + P350-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+ |
| Risk Phrases | 26/27/28 |
| Safety Phrases | S28;S45;S36/S37 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | UY6000000 |
| Packaging Group | I |
| Hazard Class | 6.1(a) |
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Acetylcholine activity in selective striatal regions supports behavioral flexibility.
Neurobiol. Learn. Mem. 91(1) , 13-22, (2009) Daily living often requires individuals to flexibly respond to new circumstances. There is considerable evidence that the striatum is part of a larger neural network that supports flexible adaptations... |
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Stress-induced immobility in rats with cholinergic supersensitivity.
Biol. Psychiatry 21(7) , 657-64, (1986) Immobility during forced swimming or after mild footshock (1 mA for 2 sec) was observed in five groups of rats. The Flinders Sensitive Line (FSL) of rats, known to be more sensitive to cholinergic ago... |
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Memory-modulatory effects of centrally acting noradrenergic drugs: possible involvement of brain cholinergic mechanisms.
Behav. Neural Biol 57(3) , 248-55, (1992) Post-training administration of the centrally acting muscarinic agonist oxotremorine (50.0 microgram/kg, ip) facilitated 48-hr retention, in mice, of a one-trial step-through inhibitory avoidance resp... |
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Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
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Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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Name: qHTS assay for measurement of the activity of small molecule inhibitors on Zika virus...
Source: NCGC
Target: N/A
External Id: ZIK097
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Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
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Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
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Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library
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|
Name: 96-well format Chlamydomonas reinhardtii Algae Gravitaxis Assay to measure the differ...
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: MH081217, Chlamydomonas reinhardtii Gravitaxis Assay to Identify Small Molecule Inhibitors of Cilia.
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Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
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Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
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| EINECS 241-388-3 |
| MFCD00013163 |
| 1-(4-[1-Pyrrolidinyl]-2-butynyl)-2-pyrrolidinone 1-(4-[1-Pyrrolidinyl]2-butynyl)-2-pyrrolidinone |
| Oxotremorine sesquifumarate,1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinonesesquifumarate |