Tanshinone IIB

Modify Date: 2026-07-13 12:05:23

Tanshinone IIB Structure
Tanshinone IIB structure
Common Name Tanshinone IIB
CAS Number 17397-93-2 Molecular Weight 310.344
Density 1.3±0.1 g/cm3 Boiling Point 536.9±50.0 °C at 760 mmHg
Molecular Formula C19H18O4 Melting Point N/A
MSDS N/A Flash Point 278.5±30.1 °C

 Use of Tanshinone IIB


Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis[1].

 Names

Name Tanshinone IIB
Synonym More Synonyms

 Tanshinone IIB Biological Activity

Description Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis[1].
Related Catalog
References

[1]. Xue-Qing Yu, et al. Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. Phytother Res. 2008 Jun;22(6):846-50.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 536.9±50.0 °C at 760 mmHg
Molecular Formula C19H18O4
Molecular Weight 310.344
Flash Point 278.5±30.1 °C
Exact Mass 310.120514
PSA 67.51000
LogP 3.80
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.606
InChIKey XDUXBBDRILEIEZ-LJQANCHMSA-N
SMILES Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCCC2(C)CO

 Safety Information

Hazard Codes Xi
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Tanshinone IIBBioassay

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Name: Inhibition of EZH2 histone methyltransferase activity in EZH2/SUZ12/EED protein compl...
Source: ChEMBL
Target: Polycomb protein EED
External Id: CHEMBL3294386
Name: Inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3) using Dabcyl-K...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2149727
Name: Time dependent inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3) ...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2150311
Name: Inhibition of chymotrypsin using N-benzoyl-L-tyrosine ethyl ester as substrate assess...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2149732
Name: Inhibition of SARS-CoV PLpro expressed in Escherichia coli (DE3) BL21 using Arg-Leu-A...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2150312
Name: Inhibition of papaya papain using N-alpha-benzoyl-L-arginine-pnitroanilide as substra...
Source: ChEMBL
Target: Papain
External Id: CHEMBL2149733
Name: Time dependent inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3)...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2150310
Name: Inhibition of Human immunodeficiency virus 1 protease at 200 uM preincubated for 10 m...
Source: ChEMBL
Target: Protease
External Id: CHEMBL2149736
Name: Non competitive inhibition of SARS-CoV 3CLpro expressed in Escherichia coli BL21 (DE3...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2150315
Name: Non competitive inhibition of SARS-CoV PLpro expressed in Escherichia coli BL21 (DE3)...
Source: ChEMBL
Target: Replicase polyprotein 1a
External Id: CHEMBL2150316
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 Synonyms

(6S)-6-(Hydroxymethyl)-1,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
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