16-BETA-HYDROXYTESTOSTERONE

Modify Date: 2024-01-10 08:32:24

16-BETA-HYDROXYTESTOSTERONE Structure
16-BETA-HYDROXYTESTOSTERONE structure
Common Name 16-BETA-HYDROXYTESTOSTERONE
CAS Number 17528-90-4 Molecular Weight 304.42400
Density 1.19g/cm3 Boiling Point 454.7ºC at 760 mmHg
Molecular Formula C19H28O3 Melting Point N/A
MSDS Chinese USA Flash Point 242.9ºC
Symbol GHS08
GHS08
Signal Word Danger

 Names

Name 16β-Hydroxytestosterone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 454.7ºC at 760 mmHg
Molecular Formula C19H28O3
Molecular Weight 304.42400
Flash Point 242.9ºC
Exact Mass 304.20400
PSA 57.53000
LogP 2.85000
Vapour Pressure 3.53E-10mmHg at 25°C
Index of Refraction 1.578

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H351-H360
Precautionary Statements P201-P281-P308 + P313
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
RIDADR NONH for all modes of transport

 Articles7

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Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: a pilot study comparing pre- and post-operative levels.

Mol. Genet. Metab. 89(4) , 381-9, (2006)

Most, but not all, studies have found that women with a high urinary 2-hydroxyestrogen (2OHE) to 16alpha-hydroxyestrone (16alphaOHE1) ratio are at reduced risk for breast cancer and have a better prog...

Permissive and suppressive effects of dexamethasone on enzyme induction in hepatocyte co-cultures.

Xenobiotica 32(8) , 653-66, (2002)

1. Steroids are known to act as permissive factors in hepatocytes. This study shows that dexamethasone (DEX) is a permissive factor for induction of CYP2B1/2, CYP3A1, CYP2A1 and probably also CYP2C11 ...

Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.

Drug Metab. Dispos. 22(4) , 584-91, (1994)

P450 2C11 from rat liver is known to metabolize testosterone to 2 alpha-, 16 alpha-, and 6 beta-hydroxytestosterone, and to androstenedione and 16 alpha-hydroxyandrostenedione. Because Waxman (J. Biol...

 Synonyms

(8R,9S,10R,13S,14S,16S,17R)-16,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one